{"id":"W2377354746","doi":"","title":"Mechanism research and effects of clock gene Per2 in K562 leukemia cells on their proliferation,differentiation and apoptosis","year":2009,"lang":"en","type":"article","venue":"Di-san junyi daxue xuebao","topic":"Circadian rhythm and melatonin","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Blood Services","funders":"","keywords":"PER2; K562 cells; Transfection; Apoptosis; Molecular biology; Biology; Cell growth; Cell cycle; Cell biology; Cell culture; Gene expression; CLOCK; Gene; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001759959,0.0003185239,0.0003166627,0.0002173164,0.0001677879,0.0002684086,0.0002024129,0.0001973393,0.0006956852],"category_scores_gemma":[0.0001295883,0.0001180276,0.0002862921,0.0002227727,0.0001760773,0.0003171279,0.0001919057,0.0002834463,0.000142077],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002799589,"about_ca_system_score_gemma":0.0001749135,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002569219,"about_ca_topic_score_gemma":0.0002708299,"domain_scores_codex":[0.9998302,0.0000228327,0.00001824991,0.0000419819,0.0000465882,0.0000400719],"domain_scores_gemma":[0.9999294,0.000007847265,0.00003000672,0.000008465446,0.0000121543,0.00001200467],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000536554,0.00006395442,0.00255986,0.0005725079,0.00003575338,0.0003117509,0.00006132385,0.0003210267,0.9841765,0.0007102456,0.0003197175,0.01033069],"study_design_scores_gemma":[0.0001316318,0.001027113,0.04132811,0.00005120176,0.0001366555,0.001435029,0.000177607,0.002714188,0.9347983,0.0005596739,0.01761522,0.00002532228],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9426455,0.04385418,0.008723076,0.0003162102,0.000217973,0.00007061063,0.0006919025,0.0001704937,0.003309981],"genre_scores_gemma":[0.983537,0.01251822,0.001547383,0.0001330979,0.00003933549,0.00007977666,0.0003662606,0.00001302173,0.001765842],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006956852,"threshold_uncertainty_score":0.002327263,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02831586844454055,"score_gpt":0.2722857288662402,"score_spread":0.2439698604216996,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}