{"id":"W2378632250","doi":"10.2147/ccid.s100697","title":"A randomized, placebo-controlled, single-blinded, split-faced clinical trial evaluating the efficacy and safety of KLOX-001 gel formulation with KLOX light-emitting diode light on facial rejuvenation","year":2016,"lang":"en","type":"article","venue":"Clinical Cosmetic and Investigational Dermatology","topic":"Dermatologic Treatments and Research","field":"Medicine","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"GDI Integrated Facility Services (Canada); Victoria Park; Klox Technologies (Canada); McGill University Health Centre; Université de Montréal","funders":"","keywords":"Medicine; Tolerability; Placebo; Facial rejuvenation; Randomized controlled trial; Adverse effect; Wrinkle; Surgery; Clinical trial; Rejuvenation; Dermatology; Internal medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.004389612,0.0002978566,0.001729155,0.0001556556,0.0003133086,0.00003708903,0.0001316844,0.0004351048,0.00004468613],"category_scores_gemma":[0.01761425,0.000132678,0.0002670143,0.0001692606,0.001522141,0.0001211008,0.00009767584,0.0004642123,0.00001735444],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004108165,"about_ca_system_score_gemma":0.000354815,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005780978,"about_ca_topic_score_gemma":0.000003333989,"domain_scores_codex":[0.993651,0.00230627,0.002419393,0.0006053963,0.0006591164,0.0003588671],"domain_scores_gemma":[0.9789361,0.01908178,0.0009292731,0.0003321736,0.0004069615,0.0003137479],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9429793,0.0008364213,0.0137225,0.00005750115,0.0006207719,0.00002450057,0.0001066315,0.000003441443,0.0001559838,0.01175165,0.0003529238,0.02938838],"study_design_scores_gemma":[0.9702078,0.00396525,0.01371181,0.0003825384,0.0006658719,0.0003136357,0.00005147407,0.004040658,0.0002617498,0.005305186,0.0008931604,0.0002008857],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9582758,0.0002706384,0.0004664364,0.03555006,0.0002475384,0.003722703,0.00000990315,0.00003674709,0.001420157],"genre_scores_gemma":[0.9961867,0.0002241954,0.001611409,0.001144457,0.0002527203,0.0001817739,0.00003962836,0.00002188108,0.0003372458],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03791087,"threshold_uncertainty_score":0.9906608,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1564775038040263,"score_gpt":0.4305368039733126,"score_spread":0.2740593001692863,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}