{"id":"W2378632250","doi":"10.2147/ccid.s100697","title":"A randomized, placebo-controlled, single-blinded, split-faced clinical trial evaluating the efficacy and safety of KLOX-001 gel formulation with KLOX light-emitting diode light on facial rejuvenation","year":2016,"lang":"en","type":"article","venue":"Clinical Cosmetic and Investigational Dermatology","topic":"Dermatologic Treatments and Research","field":"Medicine","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"GDI Integrated Facility Services (Canada); Victoria Park; Klox Technologies (Canada); McGill University Health Centre; Université de Montréal","funders":"","keywords":"Medicine; Tolerability; Placebo; Facial rejuvenation; Randomized controlled trial; Adverse effect; Wrinkle; Surgery; Clinical trial; Rejuvenation; Dermatology; Internal medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00323289,0.002207722,0.004923367,0.0006088214,0.0009002275,0.001496276,0.001401556,0.003048267,0.008882129],"category_scores_gemma":[0.003266671,0.001060314,0.001400543,0.0004357151,0.002905317,0.001618961,0.0005908143,0.002967602,0.001252464],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007472745,"about_ca_system_score_gemma":0.002536929,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004997163,"about_ca_topic_score_gemma":0.0009242865,"domain_scores_codex":[0.9983944,0.0008022243,0.0001230553,0.0003423062,0.0001358094,0.0002021649],"domain_scores_gemma":[0.9973267,0.0007580505,0.0005391206,0.000242249,0.0002500912,0.0008836898],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9842851,0.01009098,0.0001608988,0.0001884262,0.000139257,0.00001751012,0.00001921157,0.00007148549,0.001830955,0.0000506126,0.0001461122,0.002999543],"study_design_scores_gemma":[0.91769,0.08121928,0.0003568249,0.000009772646,0.00008975025,0.000009195044,0.00001003401,0.0001635123,0.0002833177,0.00005163394,0.0001098115,0.000006861158],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9848633,0.001858478,0.0007977171,0.0004491909,0.0006895892,0.009180972,0.0006009332,0.00009931518,0.001460365],"genre_scores_gemma":[0.9790239,0.0009259002,0.003104702,0.001022506,0.0006014378,0.01249353,0.0005264345,0.00002150648,0.002280009],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008882129,"threshold_uncertainty_score":0.02971369,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1564775038040263,"score_gpt":0.4305368039733126,"score_spread":0.2740593001692863,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}