{"id":"W2379025285","doi":"10.1161/hypertensionaha.116.07293","title":"Unsupervised Placental Gene Expression Profiling Identifies Clinically Relevant Subclasses of Human Preeclampsia","year":2016,"lang":"en","type":"article","venue":"Hypertension","topic":"Pregnancy and preeclampsia studies","field":"Medicine","cited_by":240,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University of Ottawa","funders":"Canadian Institutes of Health Research; University of Toronto","keywords":"Preeclampsia; Gene expression profiling; Profiling (computer programming); Gene; Gene expression; Computational biology; Biology; Placenta; Bioinformatics; Medicine; Pregnancy; Genetics; Fetus; Computer science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003241485,0.0002219895,0.0005817553,0.0000960904,0.0001739481,0.00000876312,0.0001320147,0.0001789313,0.00007055053],"category_scores_gemma":[0.0004064016,0.0001293953,0.0001974758,0.0001053782,0.0002101577,0.000160021,0.0001849883,0.0001489128,0.00004060507],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003202009,"about_ca_system_score_gemma":0.00005938677,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001074805,"about_ca_topic_score_gemma":0.000004735864,"domain_scores_codex":[0.9980693,0.0001078425,0.0006691436,0.0004396857,0.000412291,0.0003016788],"domain_scores_gemma":[0.9986222,0.000295393,0.0001941414,0.0005488258,0.000222436,0.0001169748],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005527444,0.0002115834,0.08634371,0.0001653445,0.00005600414,0.00005048262,0.0001418121,2.103314e-7,0.9101384,0.00006066128,0.001216908,0.001062151],"study_design_scores_gemma":[0.003235529,0.0005954161,0.06952399,0.002896845,0.0001493406,0.00009536878,0.0002234768,0.00002082825,0.922459,0.0003786839,0.0002226874,0.0001988385],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954445,0.001713913,0.0001920461,0.0004876648,0.0002728526,0.000483478,0.00001459096,0.000126466,0.001264447],"genre_scores_gemma":[0.9949207,0.0009753829,0.003022105,0.0001549363,0.0001407064,0.00002455934,0.0000270394,0.00003378078,0.00070075],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01681971,"threshold_uncertainty_score":0.5276586,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05333932161212306,"score_gpt":0.2989442124043794,"score_spread":0.2456048907922563,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}