{"id":"W2384087620","doi":"10.1186/s13148-016-0220-7","title":"RRx-001, an epigenetic-based radio- and chemosensitizer, has vascular normalizing effects on SCCVII and U87 tumors","year":2016,"lang":"en","type":"article","venue":"Clinical Epigenetics","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia Hospital","funders":"","keywords":"Chemosensitizer; Epigenetics; Medicine; Cancer research; Internal medicine; Oncology; Psychology; Biology; Genetics; Cytotoxicity; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001257746,0.0002480631,0.0001610079,0.0001680058,0.0000814233,0.0001200132,0.0001309174,0.0001512655,0.0008214046],"category_scores_gemma":[0.00007617654,0.00008271307,0.0001904262,0.00009867649,0.0001658786,0.00009338107,0.0000761947,0.0003061616,0.000127589],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002331628,"about_ca_system_score_gemma":0.0001607017,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001212326,"about_ca_topic_score_gemma":0.001820191,"domain_scores_codex":[0.9999279,0.00001003258,0.000005264414,0.00001541477,0.00002489287,0.00001655609],"domain_scores_gemma":[0.9999341,0.00001313859,0.00002279919,0.00000829594,0.000009538947,0.00001221085],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006341745,0.00002554199,0.0001697801,0.00002661911,0.00000372773,0.00001179525,0.000008630033,0.00008583237,0.9980099,0.00002193689,0.0000213264,0.001551558],"study_design_scores_gemma":[0.000006448362,0.0006232078,0.003970136,0.000001719533,0.00001336464,0.00007312879,0.000008347538,0.000280101,0.9943593,0.000005429516,0.0006574519,0.000001350897],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957438,0.001275838,0.001611897,0.0000366183,0.000009736958,0.00003001506,0.0001865503,0.00007211653,0.001033428],"genre_scores_gemma":[0.9954082,0.0009299506,0.001797318,0.00002356425,0.000005018233,0.00003531154,0.0003400325,0.0000147385,0.001445838],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001212326,"threshold_uncertainty_score":0.002747893,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02581703472740527,"score_gpt":0.2970578011829527,"score_spread":0.2712407664555475,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}