{"id":"W2387180628","doi":"","title":"Caspase-3: a New Target for Neurodegenerative Diseases Treatment","year":2003,"lang":"en","type":"article","venue":"PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"CAE (Canada)","funders":"","keywords":"Spinocerebellar ataxia; Caspase; Disease; Effector; Apoptosis; Caspase 3; Biology; Ataxia; Neuroscience; Cancer research; Medicine; Programmed cell death; Cell biology; Genetics; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00002940263,0.0001789722,0.0001469155,0.00001516626,0.0000664899,0.00002239263,0.00005682946,0.0001225117,0.00001001772],"category_scores_gemma":[0.00004473037,0.0001563791,0.00007129495,0.00006914537,0.00009987203,0.000002905805,0.00002077527,0.00003918935,0.000001237041],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000119889,"about_ca_system_score_gemma":0.0001075344,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002469867,"about_ca_topic_score_gemma":0.000002484046,"domain_scores_codex":[0.9991783,0.00003344352,0.0001310573,0.0004094169,0.00004421119,0.0002035503],"domain_scores_gemma":[0.9995953,0.0000125683,0.00004900528,0.0001928518,0.00003415398,0.0001160784],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005299308,0.0005505582,0.02198493,0.00008370104,0.0000741908,0.00001473503,0.00008319364,0.00001841737,0.9569655,0.001380519,0.002400535,0.0159138],"study_design_scores_gemma":[0.001230664,0.0005609528,0.0001250722,0.000007252387,0.00002166317,0.00001490133,0.00003310883,0.0000283269,0.9655669,0.0005428797,0.03166388,0.0002043856],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9915905,0.005495873,0.001553728,0.0001679975,0.0002847929,0.0004034411,0.0001571832,0.00001651404,0.0003299504],"genre_scores_gemma":[0.9905319,0.0002649049,0.006143376,0.0001411072,0.0005704441,0.0001764261,0.0004084957,0.00002040993,0.001742951],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02926335,"threshold_uncertainty_score":0.6376953,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01404550392793065,"score_gpt":0.2669597696133011,"score_spread":0.2529142656853705,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}