{"id":"W2394571710","doi":"10.5588/ijtld.15.0450","title":"&lt;I&gt;CYP7A1&lt;/I&gt;, &lt;I&gt;BAAT&lt;/I&gt; and &lt;I&gt;UGT1A1&lt;/I&gt; polymorphisms and susceptibility to anti-tuberculosis drug-induced hepatotoxicity","year":2016,"lang":"en","type":"article","venue":"The International Journal of Tuberculosis and Lung Disease","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"National Natural Science Foundation of China; National Science Foundation","keywords":"Haplotype; Genotype; Odds ratio; Tuberculosis; Medicine; Genotyping; Internal medicine; Genetics; Biology; Gene; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","sts","insufficient_payload"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.004486616,0.001293632,0.001453102,0.0009394515,0.001447615,0.0004760174,0.001582192,0.0008065971,0.001269156],"category_scores_gemma":[0.001020994,0.0009796799,0.0008678654,0.0006372504,0.001023348,0.001390772,0.0009466655,0.001403803,0.0001182513],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008634772,"about_ca_system_score_gemma":0.0005312851,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005294233,"about_ca_topic_score_gemma":0.0006220224,"domain_scores_codex":[0.9910269,0.0019904,0.002148646,0.001513814,0.00187777,0.001442453],"domain_scores_gemma":[0.992533,0.001645743,0.001259542,0.0009164705,0.001242139,0.002403082],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.003303498,0.001596773,0.01786599,0.000214599,0.002295927,0.0002870216,0.001422454,0.0001572308,0.9336477,0.004511273,0.0107687,0.02392883],"study_design_scores_gemma":[0.02053936,0.001845707,0.4735017,0.002222794,0.006203571,0.00183403,0.0002007742,0.01310798,0.1886734,0.008731104,0.2778352,0.005304334],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9623511,0.00691178,0.0002467429,0.02280544,0.003348537,0.001666073,0.001115157,0.0001563577,0.001398825],"genre_scores_gemma":[0.9849492,0.007447399,0.0001388562,0.003957161,0.002028788,0.0001586295,0.00004944603,0.0001467894,0.001123782],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7449743,"threshold_uncertainty_score":0.9999815,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03331327502129527,"score_gpt":0.330202487492712,"score_spread":0.2968892124714167,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}