{"id":"W2394766804","doi":"10.1158/1557-3265.ovca15-a33","title":"Abstract A33: Dual loss of the SWI/SNF complex ATPases SMARCA4/BRG1 and SMARCA2/BRM is highly sensitive and specific for small cell carcinoma of the ovary, hypercalcemic type.","year":2016,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Chromatin Remodeling and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"SMARCA4; Trichostatin A; Cancer research; Biology; Chromatin remodeling; Histone deacetylase; Chromatin; Histone; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009199817,0.0001367015,0.0002663214,0.00002451388,0.0001334118,0.00001342813,0.0002716693,0.0001965041,0.00003176297],"category_scores_gemma":[0.0002551662,0.0000734798,0.0001615422,0.000112196,0.001225344,0.000003426501,0.0004073788,0.000233269,0.00000140361],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003027964,"about_ca_system_score_gemma":0.0003547566,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003654067,"about_ca_topic_score_gemma":0.0001671695,"domain_scores_codex":[0.9983256,0.0002008323,0.0004317239,0.0004485393,0.0002847282,0.0003085267],"domain_scores_gemma":[0.9981523,0.0005510951,0.0001428134,0.0005341222,0.0005216423,0.00009809227],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001122404,0.0001370141,0.05928701,0.0002690184,0.00007081743,0.000002051455,0.0001123449,0.000004935193,0.9118683,0.00006412299,0.01169858,0.01536335],"study_design_scores_gemma":[0.002242637,0.000590101,0.4002526,0.0001845439,0.00003355118,0.000008991974,0.0001380736,0.00006985317,0.5816828,0.0003158013,0.0142964,0.0001846327],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950659,0.002012371,0.0000200475,0.001594744,0.0001858525,0.0004154786,0.0003812196,0.000002744248,0.0003216437],"genre_scores_gemma":[0.9962413,0.002474112,0.0001034794,0.0001711288,0.0003473222,0.00001924438,0.000006953356,0.00002162451,0.0006148125],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3409656,"threshold_uncertainty_score":0.4514831,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1763960399439519,"score_gpt":0.4095317544062311,"score_spread":0.2331357144622791,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}