{"id":"W2394766804","doi":"10.1158/1557-3265.ovca15-a33","title":"Abstract A33: Dual loss of the SWI/SNF complex ATPases SMARCA4/BRG1 and SMARCA2/BRM is highly sensitive and specific for small cell carcinoma of the ovary, hypercalcemic type.","year":2016,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Chromatin Remodeling and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"SMARCA4; Trichostatin A; Cancer research; Biology; Chromatin remodeling; Histone deacetylase; Chromatin; Histone; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002817806,0.0003192048,0.0002741443,0.0007468911,0.000213325,0.0002166318,0.0002068636,0.0003436892,0.002682275],"category_scores_gemma":[0.000242101,0.0001893556,0.0002145986,0.0003041789,0.0003351603,0.0001524639,0.0002050118,0.0002850411,0.0004414412],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002801386,"about_ca_system_score_gemma":0.0001285857,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008615682,"about_ca_topic_score_gemma":0.0009010831,"domain_scores_codex":[0.9997396,0.00003649931,0.00002752445,0.00006308514,0.00007619962,0.00005711427],"domain_scores_gemma":[0.9998763,0.00002192995,0.00003041515,0.0000156771,0.00002109134,0.00003457164],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003199085,0.00003598833,0.02473986,0.00005141594,0.00002988114,0.001650912,0.00002005543,0.00004811011,0.9695627,0.00008091501,0.0003637667,0.003096432],"study_design_scores_gemma":[0.00009593515,0.0008972991,0.3487841,0.00001599708,0.0001145756,0.04844942,0.0001077836,0.002837004,0.5903871,0.0002205108,0.008073625,0.00001666818],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945721,0.001391342,0.0015681,0.00008575569,0.0000273679,0.0000360174,0.0003430624,0.00012232,0.001853901],"genre_scores_gemma":[0.997809,0.0002076926,0.0007591395,0.00003707555,0.00000752333,0.0000162896,0.0004317837,0.00001015303,0.0007214157],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002682275,"threshold_uncertainty_score":0.008973062,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1763960399439519,"score_gpt":0.4095317544062311,"score_spread":0.2331357144622791,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}