{"id":"W2394940576","doi":"10.1016/b978-0-12-374279-7.18025-7","title":"Principles of Treatment of Primary Immunodeficiencies","year":2016,"lang":"en","type":"book-chapter","venue":"Elsevier eBooks","topic":"Immunodeficiency and Autoimmune Disorders","field":"Immunology and Microbiology","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Hypogammaglobulinemia; Primary immunodeficiency; Immunodeficiency; Medicine; Immunologic Deficiency Syndromes; IgA deficiency; Immunology; Disease; Antibody; Immune system; Common variable immunodeficiency; Intensive care medicine; Pediatrics; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001967678,0.0005348237,0.001275134,0.0002533931,0.0001309301,0.000004883273,0.0004742322,0.000583589,0.0006425578],"category_scores_gemma":[0.0000163095,0.0003804407,0.0006160409,0.00001742557,0.001285088,0.00003592457,0.0001433841,0.0001853138,0.0002505273],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001736833,"about_ca_system_score_gemma":0.0004166211,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003533019,"about_ca_topic_score_gemma":0.000001344416,"domain_scores_codex":[0.9979631,0.00005630069,0.001074497,0.0004220081,0.00008592893,0.0003981282],"domain_scores_gemma":[0.9978328,0.0001575878,0.0009305273,0.0009133535,0.000158805,0.000006888864],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000110382,0.00009041931,0.000007565663,0.0001261383,0.0004417211,0.000001915867,0.0007605433,8.308451e-7,0.1042811,0.03238022,0.000002688547,0.8617965],"study_design_scores_gemma":[0.001149952,0.000734705,0.0001348083,0.0005987576,0.000214051,0.00002163692,0.00004846878,8.813454e-8,0.02434233,0.0009555796,0.9714102,0.0003894495],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.002202659,0.1258806,0.000002848735,0.00001300867,0.0005362395,0.0004593976,0.0002056308,0.00004237867,0.8706572],"genre_scores_gemma":[0.04852641,0.001986049,0.00001794078,0.00001976944,0.000005949621,0.00002550958,0.00008688331,0.00005910776,0.9492724],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.9714075,"threshold_uncertainty_score":0.9998648,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02023598368635142,"score_gpt":0.2198589452015408,"score_spread":0.1996229615151894,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}