{"id":"W2394965243","doi":"10.1021/acsnano.5b04333","title":"Topological Linkage of DNA Tiles Bonded by Paranemic Cohesion","year":2015,"lang":"en","type":"article","venue":"ACS Nano","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Army Research Office; Division of Computing and Communication Foundations; National Institute of General Medical Sciences; Division of Emerging Frontiers in Research and Innovation; Division of Civil, Mechanical and Manufacturing Innovation; Office of Naval Research; Gordon and Betty Moore Foundation","keywords":"Catenation; Topoisomerase; DNA; Topology (electrical circuits); Crystallography; Biophysics; Chemistry; Biology; Biochemistry; Mathematics; Combinatorics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000137253,0.0001911943,0.0001381857,0.0002966379,0.0003149312,0.0005025673,0.0003463215,0.0002143861,0.002004374],"category_scores_gemma":[0.0005650944,0.0003078716,0.0001303486,0.0002116606,0.000428546,0.0005037347,0.0007434403,0.0004003519,0.000248938],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002033775,"about_ca_system_score_gemma":0.0001899612,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001744041,"about_ca_topic_score_gemma":0.0002813262,"domain_scores_codex":[0.9998387,0.00002588401,0.000007969085,0.00005149054,0.00004487549,0.00003093624],"domain_scores_gemma":[0.9997278,0.00005656919,0.00008473807,0.00004149385,0.00002870146,0.00006066673],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001102413,0.00003860283,0.000960529,0.00005508935,0.000016632,0.0001429255,0.00009325529,0.002786873,0.98738,0.003686887,0.00006428318,0.004664644],"study_design_scores_gemma":[0.00005127792,0.0008093338,0.004962633,0.00001391202,0.00003739824,0.0004149609,0.0001921625,0.02262137,0.9616005,0.003497466,0.005764061,0.00003487937],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9798436,0.00006778399,0.01793631,0.00002433714,0.00001121907,0.00002041004,0.000041978,0.00008287416,0.001971474],"genre_scores_gemma":[0.9925697,0.00004864066,0.006028974,0.00001289028,0.000002077587,0.00002855047,0.0001099537,0.00001386564,0.001185239],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002004374,"threshold_uncertainty_score":0.006705344,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01636639661123346,"score_gpt":0.2782707104865357,"score_spread":0.2619043138753022,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}