{"id":"W2395220779","doi":"10.1038/eye.2016.90","title":"Determinants of visual acuity outcomes in eyes with neovascular AMD treated with anti-VEGF agents: an instrumental variable analysis of the AURA study","year":2016,"lang":"en","type":"article","venue":"Eye","topic":"Retinal Diseases and Treatments","field":"Medicine","cited_by":54,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"","keywords":"Ranibizumab; Medicine; Visual acuity; Macular degeneration; Ophthalmology; Aura; Ophthalmoscopy; Bevacizumab; Neuro-ophthalmology; Optometry; Ophthalmic pathology; Surgery; Internal medicine; Retinal; Glaucoma; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005364853,0.0006509924,0.0008768481,0.001162191,0.000355429,0.001109242,0.0008203752,0.0005855977,0.001100397],"category_scores_gemma":[0.01448321,0.0003487908,0.002968394,0.001347254,0.0003870409,0.0005377503,0.001148344,0.001132574,0.0001480899],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005639895,"about_ca_system_score_gemma":0.0006959772,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005279861,"about_ca_topic_score_gemma":0.003526406,"domain_scores_codex":[0.9959693,0.002425813,0.0003563221,0.0005197113,0.0004148926,0.0003140312],"domain_scores_gemma":[0.9787298,0.008087899,0.008723176,0.002106116,0.0009641832,0.001388708],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005561646,0.0000494716,0.997272,0.00001382104,0.0006821895,0.00003706517,0.00001420063,0.000176161,0.00006805747,0.00003008039,0.000078736,0.001022225],"study_design_scores_gemma":[0.00005830658,0.0002988452,0.994271,0.00001115396,0.0004818172,0.0001486873,0.00007163992,0.004193306,0.0001164753,0.00009691844,0.0002414909,0.00001034901],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980818,0.0005819799,0.0005224499,0.0001081553,0.00001406146,0.00001605949,0.0005100106,0.000009853765,0.0001556765],"genre_scores_gemma":[0.9992717,0.00008071537,0.0001942551,0.000016384,0.00002322378,0.0000122781,0.0003220459,0.000003444034,0.00007595477],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005364853,"threshold_uncertainty_score":0.02837241,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01199172331636832,"score_gpt":0.31397684712932,"score_spread":0.3019851238129517,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}