{"id":"W2396344501","doi":"10.1159/000445802","title":"Genetics of Common Antipsychotic-Induced Adverse Effects","year":2016,"lang":"en","type":"review","venue":"Complex Psychiatry","topic":"Schizophrenia research and treatment","field":"Medicine","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre for Addiction and Mental Health; Queen's University","funders":"","keywords":"Tardive dyskinesia; Antipsychotic; Pharmacogenetics; Adverse effect; CYP2D6; Dyskinesia; Medicine; Pharmacogenomics; Bioinformatics; Psychiatry; Schizophrenia (object-oriented programming); Pharmacology; Biology; Genetics; Genotype; Gene; Disease; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001413992,0.0005595341,0.002453638,0.0003684184,0.00006937521,0.000008931944,0.0003629169,0.0003376026,0.0003134437],"category_scores_gemma":[0.00003811505,0.0003569872,0.001017714,0.0003661074,0.0001216209,0.00002287996,0.0001080676,0.0004169799,0.0006332174],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001137452,"about_ca_system_score_gemma":0.00106702,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007497174,"about_ca_topic_score_gemma":0.00003430884,"domain_scores_codex":[0.9974476,0.0002223729,0.0007707578,0.0005472215,0.0005081365,0.0005039182],"domain_scores_gemma":[0.9974839,0.000261941,0.0004020814,0.001344885,0.00009314066,0.0004140538],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004765287,0.0008002325,0.0007629005,0.0310786,0.000889613,0.0000611518,0.000005284758,8.544447e-9,0.000006889553,0.001244093,0.003522876,0.9611518],"study_design_scores_gemma":[0.007472387,0.00198187,0.009163044,0.06037121,0.002993936,0.0003482714,0.000006783768,0.000003707552,0.00001532916,0.001781455,0.9152479,0.0006140792],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0009898067,0.9935107,0.00001666522,0.000199662,0.001338882,0.002038018,0.00009825074,0.00006822548,0.001739824],"genre_scores_gemma":[0.0007633498,0.99217,0.005811659,0.00006083095,0.0006243947,0.00009069958,0.0001887261,0.0001079075,0.0001824234],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9605377,"threshold_uncertainty_score":0.9998882,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08669749965025539,"score_gpt":0.4063974610927812,"score_spread":0.3196999614425258,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}