{"id":"W2396421653","doi":"10.1007/978-1-4939-3052-4_3","title":"SRYTH: A New Yeast Two-Hybrid Method","year":2015,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Bioinformatics and Genomic Networks","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"National Research Council Canada; McGill University; Concordia University","funders":"","keywords":"Yeast; Protein–protein interaction; Two-hybrid screening; Saccharomyces cerevisiae; Computational biology; Candida albicans; Biology; Function (biology); Cytoplasm; Transcription factor; Protein function; Cell biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002935672,0.001686478,0.002161329,0.002030045,0.001055046,0.002345281,0.004033376,0.002074588,0.01117162],"category_scores_gemma":[0.004963552,0.0009591559,0.002553985,0.001500575,0.0006786418,0.001584335,0.003312712,0.003275574,0.009441756],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005397885,"about_ca_system_score_gemma":0.001422301,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001168294,"about_ca_topic_score_gemma":0.001940161,"domain_scores_codex":[0.997135,0.0009500855,0.0001354982,0.0005404074,0.001059473,0.0001794997],"domain_scores_gemma":[0.9976412,0.001150184,0.00008750303,0.000611207,0.0003766042,0.0001332881],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001419231,0.0005018687,0.002771289,0.001270008,0.0009879512,0.0009592854,0.000329711,0.03160009,0.1360583,0.06213099,0.04827495,0.7136964],"study_design_scores_gemma":[0.0004437784,0.0002643136,0.001976485,0.00008577546,0.0004095859,0.001217573,0.0001209048,0.7102484,0.08279818,0.07616953,0.1258236,0.0004418862],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.00162999,0.0001428196,0.9851489,0.00006434838,0.0001582809,0.0000664768,0.0005089051,0.01114727,0.001132996],"genre_scores_gemma":[0.02818745,0.000251268,0.958376,0.0002355693,0.00009417826,0.0005374597,0.002074876,0.004280062,0.005963138],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.01117162,"threshold_uncertainty_score":0.03737277,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02805894774010128,"score_gpt":0.3889480403902764,"score_spread":0.3608890926501752,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}