{"id":"W2396784827","doi":"10.1371/journal.pone.0151829","title":"Bile Acids and Dysbiosis in Non-Alcoholic Fatty Liver Disease","year":2016,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":384,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University Health Network; University of Toronto; Hospital for Sick Children","funders":"Canadian Institutes of Health Research","keywords":"Internal medicine; Fatty liver; Lithocholic acid; Steatohepatitis; Bile acid; Chenodeoxycholic acid; Gastroenterology; Cholic acid; FGF19; Dysbiosis; Deoxycholic acid; Alcoholic liver disease; Endocrinology; Medicine; Disease; Cirrhosis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000573354,0.00008366307,0.0001017838,0.00003339329,0.00003041283,0.000007580204,0.00006851605,0.00007225331,0.00004221197],"category_scores_gemma":[0.00003407268,0.00006223366,0.00002305185,0.0000401118,0.00005063263,0.000002954066,0.0000774456,0.00003558867,0.00003995798],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001211301,"about_ca_system_score_gemma":0.00003593887,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002574118,"about_ca_topic_score_gemma":0.00005765475,"domain_scores_codex":[0.9994057,0.00002142606,0.00009704423,0.0002331101,0.00005266349,0.0001900959],"domain_scores_gemma":[0.9996182,0.000006922577,0.00002378022,0.0002001407,0.00002430085,0.0001266009],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00004339658,0.0002575468,0.1350548,0.00005365265,0.00001945421,0.000003390026,0.00002174188,2.355809e-8,0.8636194,0.000007456444,0.0002088183,0.0007102548],"study_design_scores_gemma":[0.000764885,0.0001329592,0.6543542,0.000130002,0.00002753199,0.00000111089,0.000005225525,0.00000814009,0.3434967,0.00002474931,0.0009021471,0.0001523925],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983146,0.000657373,0.00002907704,0.0006284015,0.00001235947,0.0001563697,0.00004375853,0.000006157497,0.0001519514],"genre_scores_gemma":[0.9969795,0.001618661,0.0003250626,0.0003978934,0.00008606889,0.00001886683,0.00001883486,0.00001186368,0.0005431982],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5201228,"threshold_uncertainty_score":0.2537815,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02190861505894262,"score_gpt":0.2288271135479135,"score_spread":0.2069184984889709,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}