{"id":"W2397537490","doi":"","title":"New molecular assays for cancer diagnosis and targeted therapy.","year":2008,"lang":"en","type":"article","venue":"PubMed","topic":"Advanced Biosensing Techniques and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Cytodiagnostics (Canada)","funders":"","keywords":"Companion diagnostic; Multiplex; Medicine; Biomarker; Targeted therapy; Colorectal cancer; Oncology; Cancer; Biomarker discovery; Precision medicine; Personalized medicine; Lung cancer; Disease; Diagnostic test; Breast cancer; Internal medicine; Bioinformatics; Pathology; Proteomics; Biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":{"n_in":0,"stratum":"aff_core","weight":5595.2375,"opus":{"tier":"OUT","genre":"other","about_ca":false,"confidence":"high","reason":"Review of molecular assays for cancer diagnosis and targeted therapy; the object is diagnostic technology and its clinical regulation."},"gpt":{"tier":"OUT","genre":"conceptual","about_ca":false,"confidence":"high","reason":"The review concerns cancer diagnostic assays and treatments, not research methodology."},"grok":{"tier":"OUT","genre":"other","about_ca":false,"confidence":"high","reason":"Industry-oriented review of molecular diagnostic cancer assays and personalized medicine testing."}},"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002874332,0.001417115,0.001195341,0.002645369,0.0005239157,0.001847114,0.001208029,0.001925311,0.009292297],"category_scores_gemma":[0.003228635,0.0007109061,0.0008227305,0.001493242,0.001513634,0.002436662,0.001750193,0.003750892,0.008532096],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001187157,"about_ca_system_score_gemma":0.000939776,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005218429,"about_ca_topic_score_gemma":0.000928173,"domain_scores_codex":[0.9977487,0.0005466962,0.0001133408,0.0003295289,0.0011649,0.00009687984],"domain_scores_gemma":[0.9987931,0.0004142976,0.0001600395,0.0001335808,0.0003684999,0.0001304601],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003384745,0.0001737502,0.00143642,0.00313246,0.0001469074,0.0004314214,0.0001803351,0.0009474531,0.09218877,0.08477589,0.1137763,0.7024719],"study_design_scores_gemma":[0.00006337685,0.0002777909,0.001189943,0.0003891577,0.00008533918,0.001842373,0.00007233502,0.00276897,0.03711399,0.02471489,0.9314099,0.0000720368],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.004871765,0.6775953,0.2354112,0.017199,0.01004916,0.0004633363,0.002041924,0.002208203,0.05016007],"genre_scores_gemma":[0.07499111,0.4652199,0.3404408,0.0160294,0.007495387,0.001624917,0.003546592,0.00031782,0.09033398],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.009292297,"threshold_uncertainty_score":0,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0266341114469061,"score_gpt":0.2674928890821384,"score_spread":0.2408587776352323,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}