{"id":"W2397582842","doi":"10.1038/gt.2016.18","title":"Intravesical treatment of advanced urothelial bladder cancers with oncolytic HSV-1 co-regulated by differentially expressed microRNAs","year":2016,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Oncolytic virus; microRNA; Herpes simplex virus; Oncolytic adenovirus; Bladder cancer; Cancer research; Urothelium; Genetic enhancement; Cancer; Biology; Virus; Medicine; Immunology; Urinary system; Gene; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007580063,0.0003113262,0.0003230146,0.00005306712,0.00006405496,0.00001503569,0.0002820666,0.0001474305,0.0002611563],"category_scores_gemma":[0.000004959345,0.0001888288,0.0001183655,0.00008926758,0.0002733352,0.000005287833,0.00001963634,0.00004355944,0.00001250528],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001215489,"about_ca_system_score_gemma":0.0003831656,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004281319,"about_ca_topic_score_gemma":0.00009761,"domain_scores_codex":[0.9983861,0.0001344545,0.0002592528,0.0005000253,0.0002701494,0.0004500564],"domain_scores_gemma":[0.9989762,0.00002389255,0.0001198421,0.0006155837,0.0001115419,0.000152961],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01821236,0.0002800771,0.0001192175,0.000003235684,0.0004499284,0.000003478216,0.0000928033,0.00003608171,0.9024701,0.000001225992,0.0004954875,0.07783604],"study_design_scores_gemma":[0.009199654,0.01513514,0.0003255319,0.00001440936,0.00001669347,0.000004987523,0.00001522796,0.000005248903,0.9619993,0.00001611338,0.01300119,0.000266529],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963499,0.001643685,0.0007062198,0.0002637837,0.00005750184,0.0006272078,0.0002536214,0.00002103223,0.00007709373],"genre_scores_gemma":[0.9924733,0.005029544,0.0002389655,0.0001294902,0.0001930426,0.0001262925,0.0001275033,0.00007655842,0.001605324],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07756951,"threshold_uncertainty_score":0.7700213,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01199673171564297,"score_gpt":0.280383707637196,"score_spread":0.268386975921553,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}