{"id":"W2397621937","doi":"10.1158/1538-7445.compsysbio-b1-32","title":"Abstract B1-32: Genome-wide integrative analysis correlating locus-specific DNA methylation and hydroxymethylation to gene expression in normal prostate cells","year":2015,"lang":"en","type":"article","venue":"Cancer Research","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; Occupational Cancer Research Centre; Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"","keywords":"DNA methylation; Biology; Epigenetics; Epigenomics; Gene; CpG site; Gene expression; Genetics; Regulation of gene expression; Enhancer; Carcinogenesis; Methylation; Promoter","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003334958,0.000428303,0.0005228608,0.0006539028,0.0002401427,0.0003275643,0.0002955615,0.0001964902,0.001611216],"category_scores_gemma":[0.0001671965,0.0001939019,0.0004194415,0.0006935493,0.0001814596,0.00006703584,0.0002649649,0.0004772887,0.0004915093],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000239191,"about_ca_system_score_gemma":0.0003811475,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003906502,"about_ca_topic_score_gemma":0.005402696,"domain_scores_codex":[0.9997221,0.0000382034,0.00001057809,0.0001000122,0.0000845757,0.00004443318],"domain_scores_gemma":[0.9998584,0.00003133132,0.00003478416,0.0000175515,0.0000185391,0.00003930125],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001632625,0.00002455967,0.001026629,0.00003114788,0.00001793284,0.00001804504,0.00001450633,0.0001402843,0.9973533,0.00002044137,0.00007651888,0.001113383],"study_design_scores_gemma":[0.0001032446,0.001077183,0.3104884,0.00001605129,0.0001755944,0.0008100635,0.0001244868,0.007335202,0.6721199,0.0001189656,0.007589441,0.00004143113],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9758623,0.001555919,0.007798284,0.00008359052,0.00001977127,0.0001232806,0.01277246,0.0003642383,0.001420227],"genre_scores_gemma":[0.9504294,0.0008474283,0.01195893,0.0001230916,0.00001554045,0.0001811795,0.03365974,0.0001828227,0.002601861],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003906502,"threshold_uncertainty_score":0.007767498,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04829916252125738,"score_gpt":0.3565452724766632,"score_spread":0.3082461099554059,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}