{"id":"W2397716952","doi":"10.1016/j.jval.2016.03.1611","title":"Cost-Effectiveness of Pembrolizumab (Keytruda®) Versus Ipilimumab in Patients with Advanced Melanoma in Canada","year":2016,"lang":"en","type":"article","venue":"Value in Health","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"Merck Canada Inc. (Canada); Université de Montréal","funders":"","keywords":"Ipilimumab; Pembrolizumab; Medicine; Clinical trial; Internal medicine; Oncology; Cancer; Immunotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004434697,0.0002674252,0.0007048834,0.0005036137,0.0007996728,0.001243218,0.0008358657,0.0005651865,0.002727878],"category_scores_gemma":[0.003080283,0.0002135096,0.001374112,0.001444929,0.0005032684,0.0003784272,0.000459563,0.0009969942,0.00009166761],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.05137947,"about_ca_system_score_gemma":0.03317302,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.9704717,"about_ca_topic_score_gemma":0.9811999,"domain_scores_codex":[0.9992959,0.0001224416,0.00005080816,0.00007093654,0.0001547096,0.00030502],"domain_scores_gemma":[0.9986003,0.0002200341,0.0002567869,0.00001866149,0.0002890386,0.0006152252],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.05600564,0.001592121,0.7652255,0.001719337,0.004098774,0.0008946591,0.0005417607,0.01887328,0.001713919,0.003011425,0.01602533,0.1302983],"study_design_scores_gemma":[0.005474641,0.002660612,0.9627534,0.0005648559,0.003791788,0.0004053806,0.001535825,0.01571565,0.0005377647,0.0005875824,0.005862243,0.0001102022],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9812589,0.009338219,0.00006616558,0.003036185,0.00007463172,0.00008617069,0.002319127,0.000009416755,0.003811187],"genre_scores_gemma":[0.9968297,0.001606524,0.00008994377,0.0002718223,0.00002651218,0.00001289198,0.0005758131,0.000002760849,0.0005839183],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05137947,"threshold_uncertainty_score":0.3727859,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02885874383603323,"score_gpt":0.2887272278546563,"score_spread":0.2598684840186231,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}