{"id":"W2397990992","doi":"10.1007/978-1-59745-237-3_15","title":"Oncolytic Adenoviruses for Cancer Gene Therapy","year":2008,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jennerex Biotherapeutics (Canada)","funders":"","keywords":"Oncolytic virus; Oncolytic adenovirus; Biology; Genetic enhancement; Transgene; Gene; Viral replication; Vectors in gene therapy; Virus; Virology; Cancer research; Viral vector; Genetics; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007780753,0.0007565319,0.0007015701,0.0008900677,0.0004418643,0.001111423,0.0005412021,0.0005841455,0.004490887],"category_scores_gemma":[0.0003949017,0.0004436001,0.000408518,0.0008996727,0.0003718097,0.000742041,0.0006005893,0.001991594,0.00471118],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008933426,"about_ca_system_score_gemma":0.0007904367,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003597827,"about_ca_topic_score_gemma":0.0006792487,"domain_scores_codex":[0.9994742,0.00009405133,0.00003272082,0.00006200728,0.0002909391,0.00004602052],"domain_scores_gemma":[0.9998746,0.00002781719,0.00001681451,0.00002162454,0.00003286788,0.0000262622],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002492784,0.0001341617,0.0003641763,0.002149157,0.00007072536,0.0002437058,0.0002551096,0.000847703,0.5818837,0.04929981,0.01952032,0.3449821],"study_design_scores_gemma":[0.0000492252,0.0001605873,0.0002975173,0.0001768457,0.00003192289,0.0007825719,0.00003300679,0.00065259,0.1393719,0.003756842,0.8546612,0.00002586551],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.03178665,0.5707279,0.3084945,0.002130799,0.003718809,0.001031501,0.002578239,0.002157227,0.07737425],"genre_scores_gemma":[0.1640387,0.4256083,0.3029149,0.0009845754,0.0006136943,0.001225616,0.004771473,0.000336796,0.09950604],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.004490887,"threshold_uncertainty_score":0.01502347,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08375482201320289,"score_gpt":0.4735615622261098,"score_spread":0.3898067402129069,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}