{"id":"W2398323469","doi":"10.1038/ncomms11565","title":"Molecular evidence of functional progesterone withdrawal in human myometrium","year":2016,"lang":"en","type":"article","venue":"Nature Communications","topic":"Preterm Birth and Chorioamnionitis","field":"Medicine","cited_by":174,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; Canadian Institutes of Health Research","keywords":"Progesterone receptor; Myometrium; Nuclear receptor; Endocrinology; Internal medicine; Receptor; Progestogen; Chemistry; Biology; Hormone; Transcription factor; Gene; Medicine; Uterus; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001648224,0.00007405227,0.0001467045,0.0002006611,0.00005005489,0.000005438173,0.0003211172,0.0001580303,0.00004633441],"category_scores_gemma":[0.0003825796,0.00005386293,0.00005107698,0.0003900009,0.0001656225,0.0001224556,0.000135583,0.0003980066,0.000007761323],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006255318,"about_ca_system_score_gemma":0.00009057614,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001140337,"about_ca_topic_score_gemma":0.00008969208,"domain_scores_codex":[0.9992667,0.00007025139,0.00021553,0.0001246891,0.0002050299,0.0001178386],"domain_scores_gemma":[0.9983438,0.0001880242,0.00007763549,0.001142798,0.0001842111,0.00006351265],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001477975,0.000391623,0.355866,0.00007805133,0.00006028669,0.00001051777,0.0001236146,0.000001036961,0.6178997,0.0178422,0.00106978,0.006509474],"study_design_scores_gemma":[0.001957166,0.0003786785,0.9469905,0.001514217,0.00005975632,0.00005777723,0.00003481909,0.00002186095,0.04290528,0.0005792541,0.005334144,0.0001665503],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9658549,0.01566995,0.0003533384,0.01457139,0.000080169,0.0003762203,0.00001364432,0.00004628038,0.003034048],"genre_scores_gemma":[0.9982018,0.0003853505,0.0009222029,0.000250613,0.00002348012,0.00004394027,0.00002115121,0.000009255301,0.000142165],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5911245,"threshold_uncertainty_score":0.2196467,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03187547766726103,"score_gpt":0.3283812222419026,"score_spread":0.2965057445746416,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}