{"id":"W2398648203","doi":"10.3727/000000001783986387","title":"Inhibition of Cytokine Production and Cytokine-Stimulated T-Cell Activation by FK506 (Tacrolimus)1","year":2001,"lang":"en","type":"article","venue":"Cell Transplantation","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Cytokine; Ionomycin; T cell; Chemistry; Interleukin 2; Cell growth; Calcineurin; Molecular biology; Stimulation; Cell biology; Biology; Endocrinology; Internal medicine; Immunology; Immune system; Transplantation; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001039343,0.0001312379,0.00009582656,0.00004738375,0.00005629433,0.00001061884,0.00004210553,0.0001262598,0.00001380578],"category_scores_gemma":[0.00001940805,0.0001432049,0.00003636125,0.0001213253,0.00004820574,0.00001527689,0.000006817057,0.00005808341,0.000002689345],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001148217,"about_ca_system_score_gemma":0.00002296211,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001450468,"about_ca_topic_score_gemma":0.000003944076,"domain_scores_codex":[0.999177,0.00004962591,0.0002159854,0.0003005139,0.0001282186,0.0001286765],"domain_scores_gemma":[0.9995786,0.00001161628,0.0001205497,0.0001484025,0.00009039111,0.00005045785],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004990229,0.0001430203,0.002719482,0.00017273,0.000009189853,0.000003116915,0.0001520338,0.001138162,0.9945347,0.000001796347,0.0002898878,0.0003368254],"study_design_scores_gemma":[0.0009606716,0.0001694473,0.001605889,0.0000458974,0.00005544646,0.00001393403,0.00003386241,0.0001175031,0.996475,0.00003050929,0.0003439643,0.000147825],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990162,0.0001533785,0.008676526,0.00004642029,0.00007411527,0.0002480745,0.00008468345,0.00002348849,0.0005313812],"genre_scores_gemma":[0.9968719,0.0005896929,0.0002235306,0.00005085176,0.00009286378,0.00001561547,0.001940778,0.00002175979,0.0001930224],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008452995,"threshold_uncertainty_score":0.5839728,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008400387413232919,"score_gpt":0.221392008974129,"score_spread":0.2129916215608961,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}