{"id":"W2398661304","doi":"10.2337/dc16-0115","title":"Eating Behavior, Low-Frequency Functional Mutations in the Melanocortin-4 Receptor (<i>MC4R</i>) Gene, and Outcomes of Bariatric Operations: A 6-Year Prospective Study","year":2016,"lang":"en","type":"article","venue":"Diabetes Care","topic":"Bariatric Surgery and Outcomes","field":"Medicine","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"European Research Council; Institut National de la Santé et de la Recherche Médicale","keywords":"Medicine; Weight loss; Melanocortin 4 receptor; Body mass index; Internal medicine; Binge eating; Melanocortin; Obesity; Surgery; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002777851,0.0001481469,0.0003243268,0.000183205,0.0001225159,0.0000198068,0.00007527821,0.00006401908,0.0001152352],"category_scores_gemma":[0.0005815082,0.0000822968,0.00009020963,0.0004138737,0.0000594455,0.0001394511,0.00003215806,0.0001214357,0.00001867404],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006960901,"about_ca_system_score_gemma":0.0001097506,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004392012,"about_ca_topic_score_gemma":0.00005351776,"domain_scores_codex":[0.9987422,0.0001289678,0.0004031968,0.0002588785,0.0002740236,0.0001927629],"domain_scores_gemma":[0.9988966,0.0005111368,0.00008238516,0.000248035,0.0002129528,0.00004889174],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00001308211,0.000241647,0.9921748,0.00002565862,0.00006184755,0.000004751147,0.003988418,0.000002026591,0.001674036,0.0002086513,0.00002478346,0.001580306],"study_design_scores_gemma":[0.001718376,0.0002272319,0.9874697,0.00003726489,0.0002112413,0.000001856024,0.009478684,0.00000229863,0.000687675,0.000055797,0.000005608052,0.0001042506],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976214,0.0003322867,0.000009531345,0.0002760586,0.0001846749,0.00126606,0.00008151761,0.0000277997,0.0002006585],"genre_scores_gemma":[0.9986065,0.00001330122,0.0005364268,0.0001225261,0.00008814321,0.0005091475,0.00004037877,0.00001534726,0.00006825056],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005490266,"threshold_uncertainty_score":0.3355966,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01274275524809116,"score_gpt":0.255080313167288,"score_spread":0.2423375579191968,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}