{"id":"W2398661304","doi":"10.2337/dc16-0115","title":"Eating Behavior, Low-Frequency Functional Mutations in the Melanocortin-4 Receptor (<i>MC4R</i>) Gene, and Outcomes of Bariatric Operations: A 6-Year Prospective Study","year":2016,"lang":"en","type":"article","venue":"Diabetes Care","topic":"Bariatric Surgery and Outcomes","field":"Medicine","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"European Research Council; Institut National de la Santé et de la Recherche Médicale","keywords":"Medicine; Weight loss; Melanocortin 4 receptor; Body mass index; Internal medicine; Binge eating; Melanocortin; Obesity; Surgery; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001105659,0.0004887755,0.0003385633,0.0006461442,0.0004637351,0.0005741934,0.0004191202,0.0007117239,0.001378241],"category_scores_gemma":[0.002319245,0.0004273556,0.0007094591,0.0006353441,0.0004251198,0.0006483306,0.000492668,0.0008407732,0.0003269039],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002314996,"about_ca_system_score_gemma":0.0002931126,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002588069,"about_ca_topic_score_gemma":0.002397566,"domain_scores_codex":[0.9995747,0.0001340293,0.00004497571,0.0001009837,0.00007868958,0.0000667554],"domain_scores_gemma":[0.9975924,0.0003845446,0.001176494,0.000188249,0.0001673513,0.0004909658],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002475572,0.00008052457,0.999112,0.0000036304,0.00007555224,0.00004334391,0.00002303502,0.00003020576,0.00008914974,0.000003747711,0.00002642983,0.0002649023],"study_design_scores_gemma":[0.00002270965,0.0003802665,0.9989992,0.00000388373,0.00004803642,0.0002058238,0.00005800977,0.0001675087,0.00004441596,0.000008062193,0.00005809974,0.000004046038],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9996297,0.00009663587,0.00003644814,0.00001274346,0.000003024143,0.000005121948,0.0001411063,0.000001366969,0.00007392819],"genre_scores_gemma":[0.9993126,0.00006145311,0.00006168627,0.00001173001,0.00001019393,0.000008230611,0.0004051376,0.000001197756,0.0001276496],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002588069,"threshold_uncertainty_score":0.005847394,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01274275524809116,"score_gpt":0.255080313167288,"score_spread":0.2423375579191968,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}