{"id":"W2398961132","doi":"10.1021/acs.biochem.6b00427","title":"Heme Trafficking and Modifications during System I Cytochrome <i>c</i> Biogenesis: Insights from Heme Redox Potentials of Ccm Proteins","year":2016,"lang":"en","type":"article","venue":"Biochemistry","topic":"Heme Oxygenase-1 and Carbon Monoxide","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of General Medical Sciences; CancerCare Manitoba Foundation","keywords":"Heme; Thioether; Redox; Biogenesis; Cytochrome c; Hemeprotein; Cytochrome; Chemistry; Biochemistry; Biophysics; Biology; Mitochondrion; Stereochemistry; Enzyme","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001054102,0.0001355474,0.0001014198,0.00008730014,0.0001835881,0.0002882218,0.0001305023,0.0001973791,0.0004447291],"category_scores_gemma":[0.0001464483,0.0000728476,0.00009042479,0.0001092113,0.0002039218,0.0004066413,0.0001414232,0.0003050271,0.0001784531],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004383792,"about_ca_system_score_gemma":0.0001688169,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001357801,"about_ca_topic_score_gemma":0.0013904,"domain_scores_codex":[0.999963,0.000005674383,0.00000174532,0.00001003017,0.000006950908,0.00001254576],"domain_scores_gemma":[0.9999502,0.00001027466,0.00001361835,0.000004206066,0.00001080206,0.00001092482],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002180654,0.00001249068,0.002022143,0.00002696281,0.000001751099,0.0001178062,0.00008220867,0.0001238052,0.9942747,0.000467968,0.00007525252,0.002576876],"study_design_scores_gemma":[0.0000123858,0.0001797541,0.07815918,0.00001741568,0.00001662983,0.0005495338,0.0004539791,0.004372519,0.9102794,0.001141831,0.004801668,0.00001566929],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955283,0.0007720535,0.001993974,0.0001504156,0.000006506819,0.000005658114,0.00009604316,0.00002461066,0.00142249],"genre_scores_gemma":[0.997509,0.0005598392,0.0008773755,0.00003769888,0.000005190901,0.00000344969,0.0001030324,0.000007453414,0.0008968834],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001357801,"threshold_uncertainty_score":0.003180683,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007341724877707644,"score_gpt":0.2034765590376878,"score_spread":0.1961348341599802,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}