{"id":"W2399008936","doi":"10.1002/nbm.3549","title":"Differences in iron and manganese concentration may confound the measurement of myelin from <i>R</i><sub>1</sub> and <i>R</i><sub>2</sub> relaxation rates in studies of dysmyelination","year":2016,"lang":"en","type":"article","venue":"NMR in Biomedicine","topic":"Advanced Neuroimaging Techniques and Applications","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University Medical Centre; University of Toronto; McMaster University; Sunnybrook Hospital; Sunnybrook Health Science Centre","funders":"Diamond Light Source","keywords":"White matter; Chemistry; Myelin; Manganese; Analytical Chemistry (journal); Nuclear magnetic resonance; Relaxation (psychology); Magnetic resonance imaging; Biology; Physics; Chromatography; Central nervous system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006086993,0.0001523073,0.000393142,0.0001932298,0.00002938169,0.000004191771,0.00006329757,0.00007150236,0.000001584935],"category_scores_gemma":[0.000433392,0.00009136164,0.00001744223,0.0003611206,0.0005163013,0.0001024173,0.00004038095,0.0001253351,4.187086e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000110787,"about_ca_system_score_gemma":0.00004236298,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001021746,"about_ca_topic_score_gemma":0.0002605439,"domain_scores_codex":[0.9985311,0.00008026628,0.0006134083,0.0002913215,0.0003341617,0.0001497592],"domain_scores_gemma":[0.9989145,0.0003731229,0.0002908138,0.0002019805,0.0001756509,0.00004392803],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001506275,0.00009062621,0.08271244,0.0001055934,0.00001070321,0.000003509839,0.0008185956,9.135914e-7,0.8883229,0.0002277962,0.00004395111,0.02751231],"study_design_scores_gemma":[0.002459231,0.0002447344,0.4364516,0.001283934,0.00003789301,0.000004068386,0.000641724,0.0002336618,0.5558447,0.002658978,0.00004934368,0.00009014454],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9898956,0.002246342,0.0004753582,0.006544203,0.00003961496,0.0007398919,0.00001626159,0.00001917898,0.00002351964],"genre_scores_gemma":[0.9904684,0.009005563,0.0002180762,0.0001503303,0.00004408986,0.00008077096,0.00001952267,0.00001108039,0.000002110056],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3537392,"threshold_uncertainty_score":0.3725619,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07151617025963065,"score_gpt":0.3341724110686814,"score_spread":0.2626562408090508,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}