{"id":"W2399104760","doi":"10.1385/1-59745-166-5:91","title":"Construction of Capsid-Modified Recombinant Bovine Adenovirus Type 3","year":2007,"lang":"en","type":"article","venue":"Humana Press eBooks","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Defence Research and Development Canada; University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; Saskatchewan Health Research Foundation","keywords":"Capsid; Virology; Recombinant DNA; Viral vector; Biology; Vector (molecular biology); Transgene; Genetic enhancement; Virus; Adenoviridae; Gene delivery; Immune system; Gene; Mastadenovirus; HEK 293 cells; Cell biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003756911,0.0001309566,0.0001508158,0.00006985979,0.00006964799,0.00001199152,0.0002208141,0.0001384198,0.00003064602],"category_scores_gemma":[0.00003117348,0.0001290628,0.00006360823,0.00002463954,0.0001943338,0.000001962529,0.00009369225,0.0001122002,0.000004842603],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000160152,"about_ca_system_score_gemma":0.0000648528,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001459482,"about_ca_topic_score_gemma":0.0003319746,"domain_scores_codex":[0.9989388,0.00005882416,0.0002595545,0.0002696941,0.0001852998,0.0002878031],"domain_scores_gemma":[0.999193,0.00001208575,0.0001029998,0.0004527667,0.0001590208,0.00008010372],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004083195,0.00005918345,0.00003783886,0.00004308108,0.0001039882,0.000009223597,0.00008802225,0.00001337814,0.9271891,0.00206632,0.0009144558,0.06539227],"study_design_scores_gemma":[0.000769961,0.001948854,0.0001586954,0.00001205245,0.00001435386,0.00001125572,0.00002579279,0.00001128743,0.9660081,0.000216618,0.03067134,0.0001517112],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9703643,0.002419679,0.0002947998,0.000007766454,0.0002753649,0.0002837953,0.000007994703,0.0000189167,0.02632733],"genre_scores_gemma":[0.9953869,0.0002296813,0.0002646332,0.00005681323,0.0001675962,0.000009825335,0.00003370587,0.00002933634,0.003821508],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06524056,"threshold_uncertainty_score":0.5263027,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05266674045487203,"score_gpt":0.3249105509691135,"score_spread":0.2722438105142415,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}