{"id":"W2399104760","doi":"10.1385/1-59745-166-5:91","title":"Construction of Capsid-Modified Recombinant Bovine Adenovirus Type 3","year":2007,"lang":"en","type":"article","venue":"Humana Press eBooks","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Defence Research and Development Canada; University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; Saskatchewan Health Research Foundation","keywords":"Capsid; Virology; Recombinant DNA; Viral vector; Biology; Vector (molecular biology); Transgene; Genetic enhancement; Virus; Adenoviridae; Gene delivery; Immune system; Gene; Mastadenovirus; HEK 293 cells; Cell biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005466713,0.0004592273,0.0004229453,0.0005013422,0.0003435084,0.0005340633,0.0006201081,0.0004780703,0.001675056],"category_scores_gemma":[0.0004071442,0.0004672895,0.0004616428,0.000466413,0.0003385875,0.0002723963,0.0004551584,0.00118292,0.001466649],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009063619,"about_ca_system_score_gemma":0.0004575839,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001974763,"about_ca_topic_score_gemma":0.001972676,"domain_scores_codex":[0.9996365,0.00005908365,0.00004454248,0.00006625187,0.0001160176,0.000077456],"domain_scores_gemma":[0.9997751,0.00004097414,0.00004500197,0.00004361699,0.00003773253,0.00005752075],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001201377,0.00004858786,0.0002365813,0.0001143797,0.00001193582,0.00009641734,0.00008938771,0.0002965086,0.9940002,0.0009304524,0.0002411232,0.003814258],"study_design_scores_gemma":[0.00007087314,0.0003787506,0.001950943,0.00004210515,0.00004511945,0.0004121871,0.00005599479,0.002208111,0.9339372,0.0002646761,0.06059957,0.00003442696],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8030928,0.005805239,0.1667386,0.0004958329,0.0008699694,0.001324654,0.006448267,0.001176369,0.01404829],"genre_scores_gemma":[0.8127703,0.004001356,0.1418653,0.0002359406,0.00006126586,0.0004839063,0.01338741,0.000447605,0.02674691],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001974763,"threshold_uncertainty_score":0.00657618,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05266674045487203,"score_gpt":0.3249105509691135,"score_spread":0.2722438105142415,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}