{"id":"W2399445258","doi":"10.1093/nar/gkw445","title":"Sequence-dependent nanometer-scale conformational dynamics of individual RecBCD–DNA complexes","year":2016,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"Concordia University","funders":"","keywords":"RecBCD; Helicase; Nuclease; Biology; Biophysics; DNA; Dynamics (music); Base pair; Nucleotide; ATP hydrolysis; Adenosine triphosphate; Enzyme; Biochemistry; DNA repair; Physics; ATPase; RNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001553517,0.000155173,0.0002143408,0.0001840845,0.0001931424,0.000388735,0.0002829609,0.0002154149,0.001334883],"category_scores_gemma":[0.000493828,0.0001755456,0.0001155372,0.0001760967,0.0001984357,0.0003397859,0.0001748065,0.0006191417,0.0002365683],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004803698,"about_ca_system_score_gemma":0.0001212942,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00066707,"about_ca_topic_score_gemma":0.0007996552,"domain_scores_codex":[0.9998778,0.000009180735,0.000006623548,0.00004899823,0.00003782598,0.00001949396],"domain_scores_gemma":[0.9997378,0.00007781829,0.00005982751,0.0000238523,0.00003105913,0.00006958358],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000131594,0.00005285257,0.001498426,0.0000586946,0.00003457573,0.00008323477,0.0001548353,0.001719077,0.9919108,0.0003288033,0.0001475969,0.003879561],"study_design_scores_gemma":[0.00004046614,0.0003537609,0.02866042,0.00001332233,0.00004349871,0.0003374323,0.0002141792,0.05108911,0.91615,0.0004685681,0.002564488,0.00006476345],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959531,0.0002680777,0.002772036,0.00005253451,0.00001054173,0.00001076904,0.0001306342,0.00005204213,0.0007503403],"genre_scores_gemma":[0.9968714,0.0001703047,0.002034513,0.00003448165,0.000005443144,0.000022413,0.0002011616,0.00001718261,0.0006431572],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001334883,"threshold_uncertainty_score":0.00446558,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04432050842832457,"score_gpt":0.3243221923655295,"score_spread":0.2800016839372049,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}