{"id":"W2399783955","doi":"10.3109/10428194.2016.1171861","title":"Next-generation sequencing identifies a novel<i>ELAVL1–TYK2</i>fusion gene in MOLM-16, an AML cell line highly sensitive to the PIM kinase inhibitor AZD1208","year":2016,"lang":"en","type":"letter","venue":"Leukemia & lymphoma/Leukemia and lymphoma","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Institute for Cancer Research","funders":"National Institute for Health and Care Research","keywords":"Fusion gene; Gene; Biology; Kinase; DNA sequencing; Cancer research; Genetics; Computational biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002735278,0.0004767712,0.0005988171,0.0003692475,0.000695957,0.0009049609,0.0005731548,0.00492508,0.001966927],"category_scores_gemma":[0.001025847,0.0002231005,0.000412749,0.0002532054,0.0007207724,0.0004476513,0.0002120406,0.003303553,0.001225226],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001208785,"about_ca_system_score_gemma":0.0003273171,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001427611,"about_ca_topic_score_gemma":0.001924164,"domain_scores_codex":[0.9996805,0.00004614575,0.00002957545,0.00007207036,0.00008335597,0.00008844421],"domain_scores_gemma":[0.9995034,0.0002249629,0.00005229004,0.00003516096,0.00006498596,0.0001192769],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001387025,0.0002965824,0.02435235,0.0002490527,0.00009021398,0.7143017,0.0005249356,0.0008605783,0.1039581,0.004093862,0.09860368,0.05128191],"study_design_scores_gemma":[0.0003656252,0.0008669953,0.03870298,0.0001340973,0.0002314719,0.7675633,0.0007699183,0.0120727,0.05838208,0.00755093,0.1132837,0.00007616611],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6945421,0.005770967,0.006734225,0.244487,0.006229397,0.0002510752,0.001531817,0.0008220613,0.0396314],"genre_scores_gemma":[0.9402443,0.002099463,0.002986483,0.03793105,0.003588618,0.00006953206,0.000505705,0.00009546173,0.01247942],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00492508,"threshold_uncertainty_score":0.008770347,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02901257512162485,"score_gpt":0.2439034609333595,"score_spread":0.2148908858117347,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}