{"id":"W2399800228","doi":"10.1016/j.mehy.2016.05.025","title":"A re-examination of the role of the acute phase protein response in innate cancer defence","year":2016,"lang":"en","type":"article","venue":"Medical Hypotheses","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary; Dalhousie University","funders":"","keywords":"Cancer; Immune system; Cancer cell; Innate immune system; Immunology; Inflammation; Effector; Suppressor; Cytotoxic T cell; Biology; Cytokine; Cancer research; In vitro; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004992885,0.0000725052,0.0001534058,0.00003510934,0.00004909988,0.000001722455,0.0003188128,0.0001224591,0.000516193],"category_scores_gemma":[0.001127487,0.00003021843,0.000062402,0.000123905,0.0007944553,0.00004761625,0.0001179287,0.0001328087,0.000006616643],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002250828,"about_ca_system_score_gemma":0.0001362674,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002005138,"about_ca_topic_score_gemma":0.0001691003,"domain_scores_codex":[0.9989833,0.0004836068,0.0002073719,0.0001081691,0.00007394122,0.0001436514],"domain_scores_gemma":[0.9992282,0.0003949385,0.0001404112,0.000192737,0.0000344658,0.000009257701],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005701054,0.0001251817,0.001338827,0.000008193194,0.00002918025,8.195684e-7,0.0004867215,1.932805e-7,0.9596834,0.0002825194,0.00009109287,0.03738375],"study_design_scores_gemma":[0.0008440102,0.00009435847,0.01857544,0.000557596,0.00001267806,0.000003936138,0.0002621769,0.000002050602,0.9761361,0.0003981641,0.003064797,0.00004863388],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964619,0.0004022158,0.00001817843,0.002508415,0.00009951767,0.0001993684,0.0000581302,0.000006334883,0.0002459284],"genre_scores_gemma":[0.9980428,0.00006329727,0.0000071113,0.0001211158,0.000009360784,0.00002457887,3.48693e-7,0.000005754574,0.001725647],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03733512,"threshold_uncertainty_score":0.5651952,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01330780740908729,"score_gpt":0.2592590757523803,"score_spread":0.245951268343293,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}