{"id":"W2399865579","doi":"10.1038/srep25864","title":"Nuclease Footprints in Sperm Project Past and Future Chromatin Regulatory Events","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; University of Edinburgh; Wayne State University","keywords":"CTCF; Chromatin; Biology; Micrococcal nuclease; Histone; Genetics; Cell biology; Chromatin remodeling; Sperm; Pioneer factor; Enhancer; Transcription factor; Nucleosome; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005151525,0.0001283261,0.0001153492,0.00007669671,0.000088697,0.00004593446,0.0001041447,0.0001040325,0.00002155134],"category_scores_gemma":[0.00002938748,0.0000951589,0.00004850058,0.0001055689,0.0001243429,0.000005780071,0.0001546192,0.00003826804,0.000005632009],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002850698,"about_ca_system_score_gemma":0.0001065247,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009316283,"about_ca_topic_score_gemma":0.00006202648,"domain_scores_codex":[0.9986417,0.00003142168,0.000298813,0.000628679,0.0001666737,0.0002327138],"domain_scores_gemma":[0.9990554,0.000003029657,0.000152283,0.0006652002,0.00004883192,0.00007522871],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00001465272,0.00006754519,0.05951584,0.00002948207,0.00001377074,0.00007907789,0.00009365971,0.000002217375,0.9227584,0.00004577139,0.003370913,0.01400869],"study_design_scores_gemma":[0.001645273,0.0002145013,0.4483425,0.0002243338,0.00002701856,0.001125208,0.0005467149,0.0001155622,0.1625548,0.003513005,0.380671,0.001020035],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974924,0.0001525134,0.00003142721,0.0001494799,0.001343052,0.000228458,0.00000509317,0.000009681952,0.0005878467],"genre_scores_gemma":[0.9970311,0.00004279353,0.0004714791,0.00002056986,0.0002193295,0.00001304653,0.00003115793,0.00001804031,0.002152475],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7602035,"threshold_uncertainty_score":0.3880467,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005031477298356752,"score_gpt":0.2151069196218826,"score_spread":0.2100754423235258,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}