{"id":"W2400161350","doi":"10.1158/1538-7445.fbcr15-ia16","title":"Abstract IA16: Clonal evolution in breast cancer patients and patient derived xenografts","year":2016,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Somatic evolution in cancer; Cancer; Breast cancer; Biology; Population; Clonal selection; Oncology; Medicine; Cancer research; Genetics; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006908252,0.0001091585,0.0002561747,0.0003782874,0.0002220373,0.0005603851,0.0001698779,0.000375381,0.003277396],"category_scores_gemma":[0.001407879,0.0001008512,0.0001375596,0.0004130504,0.0001337157,0.0001966842,0.0002596853,0.0005368142,0.0005229266],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004660779,"about_ca_system_score_gemma":0.0001605518,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005277933,"about_ca_topic_score_gemma":0.0003825892,"domain_scores_codex":[0.9997504,0.00007513026,0.00001852734,0.00005386895,0.0000690884,0.00003295569],"domain_scores_gemma":[0.9990882,0.0004030364,0.000157227,0.0001122354,0.0001251093,0.0001142471],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.004394711,0.0007184274,0.4703876,0.0001950947,0.0001454467,0.005690814,0.000979783,0.003352489,0.3946685,0.002404828,0.01051608,0.1065463],"study_design_scores_gemma":[0.0002437639,0.004683579,0.7347823,0.00007670839,0.0001547369,0.03931585,0.0008713364,0.01254391,0.1680574,0.002388015,0.03682137,0.00006099812],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932866,0.0007319167,0.0008364481,0.0002312111,0.00003266639,0.00004116494,0.001116254,0.00004850785,0.003675339],"genre_scores_gemma":[0.995871,0.0002935881,0.0007981914,0.00009544681,0.00001284548,0.00003615056,0.001451385,0.00001643316,0.001424938],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003277396,"threshold_uncertainty_score":0.01096398,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01852678032601213,"score_gpt":0.3194277002063467,"score_spread":0.3009009198803346,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}