{"id":"W2400611835","doi":"10.1242/jcs.186098","title":"Cdk-dependent phosphorylation regulates TRF1 recruitment to PML bodies and promotes C-circle production in ALT cells","year":2016,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research","keywords":"Biology; Telomere; Phosphorylation; DNA; Transcription (linguistics); Molecular biology; Topoisomerase; RNA; Cell biology; Homologous recombination; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008184538,0.0002643364,0.0002460287,0.0001799791,0.0002082356,0.0003548312,0.0001653304,0.0001577255,0.001345411],"category_scores_gemma":[0.00009282893,0.0001178214,0.0001909826,0.0001360347,0.0001812974,0.0001804768,0.0002104131,0.0003435023,0.0007308717],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004847174,"about_ca_system_score_gemma":0.0002541038,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001470625,"about_ca_topic_score_gemma":0.001472171,"domain_scores_codex":[0.999917,0.000007700874,0.000007726364,0.00002137859,0.00001569451,0.0000304291],"domain_scores_gemma":[0.9999117,0.00001106522,0.00001954966,0.00001168972,0.000009163771,0.00003682344],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002464564,0.00004641115,0.0004534317,0.00003300287,0.000003445406,0.00007382235,0.00001261091,0.00007961224,0.9974592,0.0001299995,0.000102012,0.001359936],"study_design_scores_gemma":[0.00002712402,0.000115524,0.01443527,0.000004108618,0.00000710547,0.0001873759,0.00002561466,0.001372985,0.9816203,0.00004999301,0.002149421,0.00000521195],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945776,0.001897194,0.000986705,0.00008962929,0.00002349965,0.00001874764,0.0005703148,0.00009511381,0.001741269],"genre_scores_gemma":[0.9968159,0.0005279709,0.0005460862,0.00002765635,0.000006841588,0.00001661551,0.00052033,0.00001519619,0.001523338],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001470625,"threshold_uncertainty_score":0.004500926,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02822090766296922,"score_gpt":0.2821501196119209,"score_spread":0.2539292119489517,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}