{"id":"W2400721334","doi":"10.7150/jca.12501","title":"Staurosporine Induced Apoptosis May Activate Cancer Stem-Like Cells (CD44<sup>+</sup>/CD24<sup>-</sup>) in MCF-7 by Upregulating Mucin1 and EpCAM","year":2015,"lang":"en","type":"article","venue":"Journal of Cancer","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; National Natural Science Foundation of China; National Science Foundation","keywords":"Cancer stem cell; CD44; CD24; Cancer research; Staurosporine; Stem cell; clone (Java method); Cancer cell; Population; Epithelial cell adhesion molecule; Cancer; Biology; Apoptosis; Chemistry; Cell; Medicine; Internal medicine; Cell biology; Signal transduction; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000432763,0.0001749394,0.0001960373,0.0001404303,0.00008094201,0.0001766978,0.00009478808,0.0001649237,0.001055758],"category_scores_gemma":[0.00007895548,0.00006351765,0.0001968938,0.0001763453,0.0001010696,0.0001357163,0.00006195991,0.0002626685,0.0001848376],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002334034,"about_ca_system_score_gemma":0.0001478836,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005972013,"about_ca_topic_score_gemma":0.001586964,"domain_scores_codex":[0.9999599,0.000006244577,0.000005389392,0.000006373451,0.00001204082,0.00001003211],"domain_scores_gemma":[0.9999534,0.00001368978,0.00001111305,0.000007863493,0.000008050637,0.000005818694],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007794054,0.00002363399,0.0008453793,0.00004096862,0.000007245963,0.00004894168,0.00001720467,0.00008508347,0.9956113,0.00007876014,0.00003665902,0.003126845],"study_design_scores_gemma":[0.000007920276,0.0003230823,0.01286789,0.00000403011,0.00001613165,0.000165359,0.00002627125,0.0004603252,0.9847686,0.00005090901,0.001307632,0.000001929394],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944869,0.002067958,0.002010508,0.00007048,0.00001916904,0.00002736302,0.0003933607,0.00005642837,0.0008677926],"genre_scores_gemma":[0.9947733,0.001124356,0.001755169,0.0000659629,0.000005789512,0.00003946164,0.0005925845,0.000008252257,0.001635116],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001055758,"threshold_uncertainty_score":0.003531814,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03903204224047755,"score_gpt":0.3139342030854748,"score_spread":0.2749021608449972,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}