{"id":"W2400721334","doi":"10.7150/jca.12501","title":"Staurosporine Induced Apoptosis May Activate Cancer Stem-Like Cells (CD44<sup>+</sup>/CD24<sup>-</sup>) in MCF-7 by Upregulating Mucin1 and EpCAM","year":2015,"lang":"en","type":"article","venue":"Journal of Cancer","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; National Natural Science Foundation of China; National Science Foundation","keywords":"Cancer stem cell; CD44; CD24; Cancer research; Staurosporine; Stem cell; clone (Java method); Cancer cell; Population; Epithelial cell adhesion molecule; Cancer; Biology; Apoptosis; Chemistry; Cell; Medicine; Internal medicine; Cell biology; Signal transduction; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009248997,0.0004854394,0.001269276,0.0003817677,0.00008847134,0.00008298639,0.0002339544,0.0002307605,0.0004877698],"category_scores_gemma":[0.00005743857,0.0003979178,0.0002386809,0.0006351879,0.000119533,0.0005052807,0.000116801,0.000939538,0.000005857562],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00110992,"about_ca_system_score_gemma":0.001080372,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002714359,"about_ca_topic_score_gemma":0.0002157535,"domain_scores_codex":[0.9963598,0.0001376885,0.001210555,0.0004963327,0.001068929,0.0007267271],"domain_scores_gemma":[0.9972498,0.00009542578,0.0008641614,0.000391939,0.0005621907,0.0008364749],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.007209369,0.001095541,0.1393865,0.001348443,0.001989607,0.0003314503,0.01271276,0.03965766,0.2848064,0.00003291892,0.1282677,0.3831617],"study_design_scores_gemma":[0.02718397,0.001988684,0.007038594,0.003497149,0.001642283,0.0002476564,0.00762924,0.003184425,0.5390657,0.00007845464,0.4069463,0.001497564],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9857101,0.009387856,0.00004184665,0.0030294,0.0007335632,0.0004671709,0.0001069945,0.00002462715,0.0004984483],"genre_scores_gemma":[0.9895477,0.00440701,0.0006468709,0.001067992,0.001170781,0.0000365928,0.00000620957,0.0001076377,0.003009239],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3816642,"threshold_uncertainty_score":0.9998473,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03903204224047755,"score_gpt":0.3139342030854748,"score_spread":0.2749021608449972,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}