{"id":"W2401230816","doi":"10.1016/j.joca.2016.05.013","title":"Integrin α1β1 protects against signs of post-traumatic osteoarthritis in the female murine knee partially via regulation of epidermal growth factor receptor signalling","year":2016,"lang":"en","type":"article","venue":"Osteoarthritis and Cartilage","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":false,"ca_institutions":"Alberta Bone and Joint Health Institute; University of Calgary","funders":"Faculty of Kinesiology, University of Calgary; Canadian Institutes of Health Research; National Institutes of Health; U.S. Department of Health and Human Services","keywords":"Osteoarthritis; Erlotinib; Cartilage; Epidermal growth factor receptor; EGFR inhibitors; Integrin; Medicine; Immunohistochemistry; Internal medicine; Cancer research; Endocrinology; Receptor; Pathology; Anatomy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000487854,0.000365823,0.0007820795,0.000227843,0.00009886679,0.00002918526,0.0001386643,0.0002097674,0.0002667587],"category_scores_gemma":[0.000217786,0.000246333,0.0002261363,0.0002884241,0.0002513037,0.0003175156,0.00006411005,0.0001988617,0.00002029969],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000046868,"about_ca_system_score_gemma":0.00008950067,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003290748,"about_ca_topic_score_gemma":0.0006607537,"domain_scores_codex":[0.9972679,0.0002733963,0.0009583045,0.0004645316,0.0005353307,0.0005005357],"domain_scores_gemma":[0.9985352,0.0002579126,0.000352287,0.0004055066,0.0002779457,0.000171221],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003814879,0.0001753087,0.002471009,0.0002069511,0.000007604557,0.00006958725,0.001935837,8.235764e-7,0.8141089,0.0002868779,0.000007646744,0.1803479],"study_design_scores_gemma":[0.009637134,0.01193831,0.004043323,0.002973175,0.00006578279,0.0001238973,0.001375828,0.00000420574,0.9690076,0.0003075261,0.0001851246,0.0003381192],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947282,0.001570773,0.0001505714,0.000510511,0.0001403783,0.002012253,0.0001599783,0.00004553836,0.0006817601],"genre_scores_gemma":[0.9985167,0.0002069931,0.0004836135,0.0001260687,0.0001224554,0.0002363665,0.00006687412,0.00004881889,0.0001921239],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1800098,"threshold_uncertainty_score":0.9999989,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.014982377436175,"score_gpt":0.2294372900873337,"score_spread":0.2144549126511587,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}