{"id":"W2401286955","doi":"10.1007/978-1-60761-588-0_11","title":"siRNA Specific Delivery System for Targeting Dendritic Cells","year":2010,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Gene silencing; In vivo; Dendritic cell; Cell biology; CD40; In vitro; Immune system; Small interfering RNA; Chemistry; Biology; Transfection; Immunology; Cell culture; Cytotoxic T cell; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002320191,0.0004012886,0.0003168293,0.0003437097,0.0002228808,0.0003436512,0.0002768188,0.0005153332,0.001652495],"category_scores_gemma":[0.0001736302,0.0001943975,0.0002235101,0.0001824092,0.0001423606,0.0002401751,0.000255332,0.000596276,0.001637549],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003679035,"about_ca_system_score_gemma":0.000356253,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002392937,"about_ca_topic_score_gemma":0.0003172598,"domain_scores_codex":[0.9997359,0.00004044624,0.00003123414,0.00007272836,0.00008625594,0.0000334262],"domain_scores_gemma":[0.9999336,0.00001037225,0.00001581367,0.000007982986,0.00002222448,0.0000100462],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003524562,0.0000184585,0.00004260623,0.0001550559,0.000005516061,0.0000535392,0.00001774568,0.00007974129,0.988473,0.000497899,0.0004623162,0.0101588],"study_design_scores_gemma":[0.00002086208,0.0002474599,0.0002384931,0.00001412787,0.00002353178,0.0004283572,0.000007098588,0.001411142,0.9605972,0.00009170486,0.03690983,0.00001031058],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.3718296,0.02889646,0.562507,0.001324687,0.001148409,0.00257533,0.003009748,0.003476494,0.02523228],"genre_scores_gemma":[0.7331959,0.01302397,0.2136521,0.00112725,0.0001906766,0.002346006,0.003799225,0.0002433921,0.03242143],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.001652495,"threshold_uncertainty_score":0.005528212,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01651548274885336,"score_gpt":0.333847895504648,"score_spread":0.3173324127557947,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}