{"id":"W2401396814","doi":"10.1038/srep13462","title":"Expression of hepatic Fibroblast Growth Factor 19 is enhanced in Primary Biliary Cirrhosis and correlates with severity of the disease","year":2015,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Fibroblast Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":96,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Fundacja na rzecz Nauki Polskiej","keywords":"FGF19; Farnesoid X receptor; Cholesterol 7 alpha-hydroxylase; Cholestasis; Internal medicine; Cirrhosis; Primary biliary cirrhosis; Fibroblast growth factor; FGF21; Liver disease; Endocrinology; Medicine; Gastroenterology; Chronic liver disease; Bile acid; Biology; Receptor; Gene; Nuclear receptor; Biochemistry; Transcription factor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003838082,0.0001184996,0.0001638391,0.00007539347,0.00005192835,0.00002461746,0.000150585,0.00006817084,0.00001224407],"category_scores_gemma":[0.0003493962,0.00007689968,0.00005183162,0.0002864994,0.0004991507,0.00001538967,0.0002980879,0.0000825598,4.728311e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002458845,"about_ca_system_score_gemma":0.0004232863,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005050826,"about_ca_topic_score_gemma":0.00002120684,"domain_scores_codex":[0.9984477,0.00008747293,0.0003201691,0.0004945003,0.0004630715,0.0001871219],"domain_scores_gemma":[0.9986926,0.00001723598,0.000236654,0.0006771744,0.0002046383,0.0001717323],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009376235,0.00005630208,0.3290711,0.000148809,0.000005598499,0.00000682288,0.000210299,0.0000110425,0.6696637,4.468253e-7,0.0006904177,0.00004163628],"study_design_scores_gemma":[0.0001966959,0.00008136267,0.1967024,0.0001878222,0.000005331529,0.00001041321,0.00004199299,0.00002237508,0.8023584,0.0002492011,0.00005944677,0.00008458721],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990425,0.0001821707,0.00005333267,0.00004313627,0.0002014408,0.0003256253,0.00002362867,0.000004163312,0.0001240444],"genre_scores_gemma":[0.9994418,0.000007438204,0.0001553138,0.00001144015,0.000008389422,0.00001235323,0.00003295356,0.00001151474,0.0003187894],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1326946,"threshold_uncertainty_score":0.3135878,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0101711146256252,"score_gpt":0.2343705581997866,"score_spread":0.2241994435741614,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}