{"id":"W2401396814","doi":"10.1038/srep13462","title":"Expression of hepatic Fibroblast Growth Factor 19 is enhanced in Primary Biliary Cirrhosis and correlates with severity of the disease","year":2015,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Fibroblast Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":96,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Fundacja na rzecz Nauki Polskiej","keywords":"FGF19; Farnesoid X receptor; Cholesterol 7 alpha-hydroxylase; Cholestasis; Internal medicine; Cirrhosis; Primary biliary cirrhosis; Fibroblast growth factor; FGF21; Liver disease; Endocrinology; Medicine; Gastroenterology; Chronic liver disease; Bile acid; Biology; Receptor; Gene; Nuclear receptor; Biochemistry; Transcription factor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001107489,0.0001631193,0.0002734593,0.0004989709,0.0001704258,0.0001871585,0.00005661351,0.0001638,0.001256078],"category_scores_gemma":[0.0003879949,0.0001416614,0.000124689,0.0003264323,0.0002314533,0.00008155913,0.0001770152,0.0002223644,0.0001910952],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001509216,"about_ca_system_score_gemma":0.00007527125,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004200357,"about_ca_topic_score_gemma":0.0005102752,"domain_scores_codex":[0.9998676,0.00002986888,0.00001428367,0.00002498727,0.00003919422,0.00002403942],"domain_scores_gemma":[0.9996586,0.00005128888,0.0001718201,0.00001754938,0.000029688,0.00007100886],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002113717,0.00005480525,0.8579974,0.00008160322,0.00007716178,0.001474541,0.0001142293,0.00008190588,0.1301462,0.00004412398,0.0001396537,0.00767475],"study_design_scores_gemma":[0.000006487323,0.00014449,0.9950229,0.000002332607,0.0000193421,0.001443144,0.00003712537,0.00008658248,0.003022194,0.00002066911,0.0001928666,0.000001817449],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989682,0.0005381325,0.0001173819,0.00001688262,0.000002236999,0.000003303558,0.00006533741,0.000006663932,0.0002818782],"genre_scores_gemma":[0.9995356,0.0001396501,0.00009456365,0.000009054561,0.00000606311,0.000003589517,0.00007418585,0.000001239578,0.0001360512],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001256078,"threshold_uncertainty_score":0.004202008,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0101711146256252,"score_gpt":0.2343705581997866,"score_spread":0.2241994435741614,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}