{"id":"W2401402628","doi":"10.1038/srep26811","title":"Interconnection of post-transcriptional regulation: The RNA-binding protein Hfq is a novel target of the Lon protease in Pseudomonas aeruginosa","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Canada Research Chairs; Cystic Fibrosis Canada; Fundación Ramón Areces","keywords":"Proteases; Mutant; Biology; Cell biology; Pseudomonas aeruginosa; Protease; Transcriptional regulation; RNA; Stable isotope labeling by amino acids in cell culture; Swarming motility; RNA-binding protein; Gene; Microbiology; Gene expression; Quorum sensing; Genetics; Biochemistry; Virulence; Proteomics; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002385763,0.0003312695,0.0002469693,0.0002003055,0.0001645935,0.000544673,0.0001677228,0.0003349721,0.0008265616],"category_scores_gemma":[0.0001681811,0.0001008182,0.000253686,0.0001485107,0.0003331015,0.0003939825,0.000252325,0.0003950614,0.0003349836],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003453274,"about_ca_system_score_gemma":0.0002217443,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005934977,"about_ca_topic_score_gemma":0.0005779832,"domain_scores_codex":[0.9997782,0.00003399971,0.00001553595,0.0000743839,0.00006211334,0.00003583839],"domain_scores_gemma":[0.9998425,0.00002729223,0.0000486544,0.00002226117,0.00003444502,0.00002479295],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002502091,0.00000745909,0.0003985932,0.00003282804,0.000002867147,0.00006689943,0.00001226945,0.00002825822,0.9976081,0.00009663965,0.00002115354,0.00169999],"study_design_scores_gemma":[0.000009957243,0.0002599239,0.04603922,0.00001181235,0.00002643838,0.0006204296,0.00008078157,0.00297634,0.9451568,0.0004514546,0.004352079,0.00001478551],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9687355,0.0070111,0.0206001,0.0005668227,0.00008552679,0.00004177695,0.0004377487,0.0002814553,0.002239883],"genre_scores_gemma":[0.9915935,0.001286347,0.004587259,0.0001089396,0.00003394329,0.00002104313,0.0002863806,0.00002649478,0.002056049],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008265616,"threshold_uncertainty_score":0.002765119,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009124867124350986,"score_gpt":0.2142390308109164,"score_spread":0.2051141636865654,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}