{"id":"W2401402628","doi":"10.1038/srep26811","title":"Interconnection of post-transcriptional regulation: The RNA-binding protein Hfq is a novel target of the Lon protease in Pseudomonas aeruginosa","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Canada Research Chairs; Cystic Fibrosis Canada; Fundación Ramón Areces","keywords":"Proteases; Mutant; Biology; Cell biology; Pseudomonas aeruginosa; Protease; Transcriptional regulation; RNA; Stable isotope labeling by amino acids in cell culture; Swarming motility; RNA-binding protein; Gene; Microbiology; Gene expression; Quorum sensing; Genetics; Biochemistry; Virulence; Proteomics; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006576493,0.00009363829,0.0001048307,0.00006856185,0.00008379517,0.00001906613,0.0001858625,0.0001451184,0.00004775041],"category_scores_gemma":[0.0001378681,0.00004914299,0.00009929989,0.0002223886,0.0004078795,0.000006616468,0.0001049681,0.00005923126,8.983216e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001549415,"about_ca_system_score_gemma":0.0001327122,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002692202,"about_ca_topic_score_gemma":0.00005217368,"domain_scores_codex":[0.9988319,0.00004229041,0.0004073323,0.0003708897,0.0002007259,0.0001468815],"domain_scores_gemma":[0.9988473,0.000004515811,0.0003309418,0.0006014704,0.0001942821,0.00002148165],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004185234,0.00007086004,0.002147763,0.0000146867,0.00001124692,9.621313e-7,0.00005442316,0.00000347811,0.9966908,0.0001548123,0.0001332454,0.0006758544],"study_design_scores_gemma":[0.0002146564,0.00007326055,0.0056213,0.00007726884,0.000004759133,0.00005312461,0.0000312228,0.000006199953,0.9851915,0.001008482,0.007647884,0.00007040567],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960614,0.00004398972,0.0004160242,0.001702064,0.001107233,0.0005705951,0.00003015308,0.000004094207,0.00006446537],"genre_scores_gemma":[0.9983629,0.000002484839,0.0003942883,0.00001675735,0.0000494554,0.00003334898,0.00002178595,0.000007024052,0.001111944],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01149938,"threshold_uncertainty_score":0.2003993,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009124867124350986,"score_gpt":0.2142390308109164,"score_spread":0.2051141636865654,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}