{"id":"W2401517553","doi":"10.1016/j.clgc.2016.05.019","title":"Molecular Dissection of Complete Response to Receptor Tyrosine Kinase Inhibition in Type II Papillary Renal Cell Carcinoma","year":2016,"lang":"en","type":"article","venue":"Clinical Genitourinary Cancer","topic":"Renal cell carcinoma treatment","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Cancer Agency; University of British Columbia","funders":"","keywords":"Medicine; Papillary renal cell carcinomas; Leiomyomatosis; Fumarase; Germline mutation; Cancer research; Tyrosine kinase; Renal cell carcinoma; Metastasis; Pathogenesis; Tyrosine-kinase inhibitor; Germline; Pathology; Internal medicine; Carcinoma; Oncology; Cancer; Mutation; Receptor; Gene; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005227985,0.0002313794,0.0005218142,0.0002076049,0.0000503867,0.000004327498,0.00007280194,0.000179576,0.0004084508],"category_scores_gemma":[0.000270631,0.0001681808,0.0002125047,0.0004307649,0.0001244572,0.00006191594,0.000141792,0.0002100757,0.00007963231],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000412981,"about_ca_system_score_gemma":0.0002824161,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007408886,"about_ca_topic_score_gemma":0.00001306673,"domain_scores_codex":[0.9976292,0.0003834253,0.0008187236,0.0005293044,0.0003218378,0.0003175723],"domain_scores_gemma":[0.9984631,0.0002804067,0.0001785153,0.000506805,0.0002384437,0.0003327291],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.02246317,0.0007350491,0.04191567,0.0000744576,0.00002774128,0.0009960834,0.00007262098,0.00002810658,0.9250375,0.000002772581,0.002481608,0.006165208],"study_design_scores_gemma":[0.004444365,0.009373518,0.4507689,0.0004616285,0.00009243232,0.00004076281,0.00002584108,0.00001061567,0.5293796,0.00002060577,0.005154361,0.0002273564],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939998,0.001466692,0.00003884867,0.002906131,0.0005045535,0.0006551365,0.00005948331,0.00003079693,0.0003385697],"genre_scores_gemma":[0.9971583,0.0003182253,0.0005289137,0.0004133759,0.0003860923,0.00007432485,0.00002995814,0.00004419332,0.001046623],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4088532,"threshold_uncertainty_score":0.6858215,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04906943625754717,"score_gpt":0.335764516210077,"score_spread":0.2866950799525298,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}