{"id":"W2401592760","doi":"10.7554/elife.10607","title":"PHF13 is a molecular reader and transcriptional co-regulator of H3K4me2/3","year":2016,"lang":"en","type":"article","venue":"eLife","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Structural Genomics Consortium","funders":"Max-Planck-Gesellschaft; Ministero dello Sviluppo Economico; Fundação de Amparo à Pesquisa do Estado de São Paulo; Bundesministerium für Gesundheit; European Federation of Pharmaceutical Industries and Associations; Novartis Pharma; Wellcome Trust; Ontario Ministry of Economic Development and Innovation; Genome Canada; Deutsche Krebshilfe; Pfizer","keywords":"Chromatin; Biology; Cell biology; ChIA-PET; ChIP-sequencing; PRC2; DNA; Transcriptional regulation; RNA; Chromatin immunoprecipitation; Chromatin remodeling; Genetics; Gene; Gene expression; Promoter; Histone H3","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001666173,0.0003488011,0.0003124266,0.0003611477,0.000571472,0.0004707731,0.0003853126,0.0004817103,0.002419985],"category_scores_gemma":[0.0002240942,0.0002522625,0.0003814233,0.0003129534,0.0004088513,0.0002785308,0.0004450391,0.0003756205,0.0009035678],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007456484,"about_ca_system_score_gemma":0.0004138168,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002600347,"about_ca_topic_score_gemma":0.002878791,"domain_scores_codex":[0.9997992,0.00001364007,0.000008500049,0.00006703753,0.00006892303,0.00004284968],"domain_scores_gemma":[0.9999204,0.00001000376,0.00001779066,0.00001060937,0.00001659226,0.00002468936],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003227388,0.0000222497,0.00375084,0.00007034701,0.00002022655,0.0002931891,0.00002089871,0.0003656969,0.984866,0.0005856961,0.0003849323,0.009297276],"study_design_scores_gemma":[0.00002094339,0.00007253365,0.03173196,0.00001232124,0.00001757926,0.00109586,0.00003590587,0.002594809,0.9546963,0.000351303,0.00935663,0.00001389844],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9507414,0.004496418,0.03439225,0.0004346188,0.0001302765,0.00005868607,0.002450789,0.0007392558,0.006556415],"genre_scores_gemma":[0.9818731,0.0006409201,0.007503473,0.00008307592,0.0000130681,0.00002361746,0.00156222,0.00004930575,0.008251209],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002600347,"threshold_uncertainty_score":0.008095622,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005665653197852076,"score_gpt":0.2232573837652399,"score_spread":0.2175917305673878,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}