{"id":"W2401629352","doi":"10.2196/resprot.5641","title":"A Decision Aid for Women Considering Neoadjuvant Systemic Therapy for Operable Invasive Breast Cancer: Development and Protocol of a Phase II Evaluation Study (ANZ1301 DOMINO)","year":2016,"lang":"en","type":"article","venue":"JMIR Research Protocols","topic":"Patient-Provider Communication in Healthcare","field":"Health Professions","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Friends of The Mater Foundation; Mater Foundation; Breast Cancer Trials; Hunter New England Local Health District","keywords":"Neoadjuvant therapy; Medicine; Breast cancer; Systemic therapy; Decision aids; Decision tree; Protocol (science); Oncology; Cancer; Intensive care medicine; Internal medicine; Computer science; Alternative medicine; Pathology; Artificial intelligence","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.07078248,0.001471913,0.001741483,0.001345991,0.001652144,0.001582039,0.001842169,0.002579398,0.01168563],"category_scores_gemma":[0.05117267,0.001012751,0.001653023,0.001428714,0.001691806,0.001198937,0.002000836,0.002658888,0.002382878],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003324867,"about_ca_system_score_gemma":0.02052753,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001064562,"about_ca_topic_score_gemma":0.002429945,"domain_scores_codex":[0.9481959,0.04488882,0.002688438,0.0008835535,0.00217581,0.00116753],"domain_scores_gemma":[0.9752255,0.009631364,0.003846818,0.002301627,0.006484758,0.00250999],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"not_applicable","study_design_scores_codex":[0.4984643,0.06791873,0.01493924,0.03238076,0.001206423,0.0007299255,0.005965181,0.006594214,0.009907891,0.009101022,0.04089508,0.3118973],"study_design_scores_gemma":[0.5965158,0.163179,0.03213951,0.007656167,0.0009588188,0.0002977203,0.002298242,0.005092868,0.005378596,0.004101564,0.1821236,0.0002580313],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.01391303,0.0001522605,0.002504489,0.0003393789,0.00009427798,0.980624,0.00084131,0.0000301873,0.001501169],"genre_scores_gemma":[0.005897013,0.0001160309,0.007615819,0.0002173685,0.00002014399,0.9854091,0.0002916419,0.000003928216,0.0004289268],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.07078248,"threshold_uncertainty_score":0.374338,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.6382911041048368,"score_gpt":0.658781480719477,"score_spread":0.02049037661464015,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}