{"id":"W2401815452","doi":"10.7150/jca.14274","title":"Warburg Effect - a Consequence or the Cause of Carcinogenesis?","year":2016,"lang":"en","type":"review","venue":"Journal of Cancer","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":141,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Warburg effect; Glycolysis; Carcinogenesis; Anaerobic glycolysis; Cancer; Citric acid cycle; Carbohydrate metabolism; Cancer cell; Lactic acid; Cancer research; Biology; Chemistry; Biochemistry; Cell biology; Enzyme; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005038593,0.0002893514,0.001231182,0.00007659371,0.00003978333,0.00001328873,0.0004896153,0.0002534201,0.00009474252],"category_scores_gemma":[0.0001746718,0.0001120905,0.0007741062,0.0001179273,0.0001850783,0.000004073368,0.00007415836,0.0002090472,0.000002695383],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005565661,"about_ca_system_score_gemma":0.002024004,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000272237,"about_ca_topic_score_gemma":0.00005129488,"domain_scores_codex":[0.9983742,0.0002524565,0.0006901503,0.0001936374,0.0002660521,0.0002234699],"domain_scores_gemma":[0.9978705,0.0001117552,0.001253403,0.0004086563,0.0002549566,0.0001007371],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002123083,0.00001484809,0.00001741384,0.002486105,0.0009118289,0.00002346397,0.00001400842,0.000001450026,0.003738075,0.000004573188,0.009484162,0.9830918],"study_design_scores_gemma":[0.0004663339,0.0002633273,0.00001281625,0.004553628,0.001408876,0.0006515219,0.000002648026,3.840998e-8,0.004428889,0.000004201953,0.9880401,0.0001676485],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0008267579,0.9962007,0.00003148319,0.00006224029,0.00240997,0.0002869484,0.0001114276,0.000001467875,0.00006895662],"genre_scores_gemma":[0.0001856659,0.993367,0.00001902475,0.00008819379,0.004646037,0.0000432808,0.000003137929,0.00003927917,0.001608364],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9829241,"threshold_uncertainty_score":0.4570918,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03688313770848672,"score_gpt":0.3703188934212257,"score_spread":0.333435755712739,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}