{"id":"W2402732438","doi":"10.1385/0-89603-480-1:17","title":"Design of Bacterial Hosts for lac-Based Expression Vectors","year":2003,"lang":"en","type":"article","venue":"Humana Press eBooks","topic":"Bacteriophages and microbial interactions","field":"Environmental Science","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Medical Research Council; Cystic Fibrosis Foundation","keywords":"Lac repressor; Complementation; Plasmid; lac operon; Repressor; Biology; Escherichia coli; Promoter; Genetics; Expression vector; Gene; Overproduction; Vector (molecular biology); Molecular biology; Recombinant DNA; Gene expression; Phenotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001173322,0.0007802626,0.0007398821,0.0009168783,0.000550763,0.00117578,0.0009632068,0.0007381218,0.001820869],"category_scores_gemma":[0.0008502594,0.0006776726,0.000298429,0.0009971358,0.0003670755,0.0005788427,0.0006257542,0.001744737,0.003799497],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000579501,"about_ca_system_score_gemma":0.0005089874,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002289304,"about_ca_topic_score_gemma":0.0004601627,"domain_scores_codex":[0.999112,0.0002187432,0.0001423556,0.0001317438,0.0002676435,0.0001275965],"domain_scores_gemma":[0.9996493,0.00007822442,0.00006563522,0.00004855657,0.00006904966,0.00008932776],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001963442,0.0001858643,0.0003478412,0.000450279,0.00001823647,0.0001820724,0.0001272504,0.000868289,0.9807599,0.004997435,0.001036578,0.01082994],"study_design_scores_gemma":[0.0001122453,0.0005492815,0.0008061689,0.0001345504,0.00004412601,0.0004845145,0.0001109235,0.002973749,0.9239041,0.0009627235,0.06987432,0.00004326036],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.4633828,0.01895639,0.482191,0.001322237,0.0009360954,0.005468354,0.008221573,0.004049325,0.01547218],"genre_scores_gemma":[0.4406608,0.01581842,0.5067919,0.0003832904,0.0001558161,0.003305834,0.01595093,0.000729832,0.01620323],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.001820869,"threshold_uncertainty_score":0.006205142,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05271770644561644,"score_gpt":0.2656408693826357,"score_spread":0.2129231629370193,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}