{"id":"W2403314208","doi":"10.1385/1-59259-145-0:109","title":"Genetic Testing in Familial Melanoma: Epidemiologic/Genetic Assessment of Risks and Role ofCDKN2A Analysis","year":2003,"lang":"en","type":"article","venue":"Humana Press eBooks","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Penetrance; CDKN2A; Melanoma; Germline mutation; Disease; Cancer; Genetics; Genetic testing; Medicine; Notice; Pancreatic cancer; Mutation; Biology; Gene; Internal medicine; Phenotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001889561,0.0004730702,0.0002876335,0.003085437,0.0005607765,0.0006444686,0.000574647,0.000841012,0.001215506],"category_scores_gemma":[0.007002101,0.0002297773,0.000210981,0.002221956,0.0005124496,0.0007142292,0.0006337421,0.0005831145,0.0002209042],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003112686,"about_ca_system_score_gemma":0.0003037149,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003799271,"about_ca_topic_score_gemma":0.002577717,"domain_scores_codex":[0.9987075,0.0006738334,0.0001200867,0.0001846767,0.000213819,0.000100033],"domain_scores_gemma":[0.9975989,0.001031339,0.0005848096,0.0001272177,0.0003325932,0.0003250275],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00008851793,0.00003735909,0.994477,0.00001066797,0.00002079287,0.001553159,0.00005586842,0.00008246609,0.0002693895,0.0000945786,0.0001392486,0.003171067],"study_design_scores_gemma":[0.00001369636,0.0002587026,0.9690862,0.00008885,0.0001102929,0.02514704,0.0007042452,0.002274748,0.0004912052,0.0006542417,0.001153831,0.00001693389],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9891977,0.004551396,0.001051414,0.0008529327,0.00002287082,0.00003181343,0.0003461591,0.0000239547,0.003921678],"genre_scores_gemma":[0.9980895,0.0007816153,0.0007415943,0.00009430139,0.00003684913,0.000007072327,0.0001140478,0.000004432833,0.0001305992],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003799271,"threshold_uncertainty_score":0.009993076,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0721409617240599,"score_gpt":0.3264299703934754,"score_spread":0.2542890086694155,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}