{"id":"W2403822861","doi":"10.1016/j.jnutbio.2016.05.004","title":"Sulforaphane effects on postinfarction cardiac remodeling in rats: modulation of redox-sensitive prosurvival and proapoptotic proteins","year":2016,"lang":"en","type":"article","venue":"The Journal of Nutritional Biochemistry","topic":"Genomics, phytochemicals, and oxidative stress","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":false,"ca_institutions":"NOSM University; Lakehead University; St. Boniface Hospital","funders":"Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul; Conselho Nacional de Desenvolvimento Científico e Tecnológico","keywords":"Sulforaphane; Protein kinase B; Oxidative stress; Cardiac function curve; Chemistry; p38 mitogen-activated protein kinases; Superoxide dismutase; Internal medicine; MAPK/ERK pathway; Kinase; Ventricular remodeling; Pharmacology; Endocrinology; Apoptosis; Medicine; Myocardial infarction; Biochemistry; Heart failure","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001754651,0.0008431206,0.0005923462,0.0005549042,0.0003535702,0.0002296739,0.0002444949,0.0005088528,0.001968226],"category_scores_gemma":[0.0001774588,0.000327018,0.0004185891,0.0002357859,0.0007172648,0.0005586945,0.0002048957,0.001270715,0.0001572283],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003143205,"about_ca_system_score_gemma":0.0004765743,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009698549,"about_ca_topic_score_gemma":0.002094676,"domain_scores_codex":[0.9998891,0.00001831353,0.000008170297,0.00002595616,0.0000152453,0.00004307192],"domain_scores_gemma":[0.9997925,0.00001611677,0.00005611692,0.00002703653,0.00001986657,0.00008833307],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01649842,0.0006927764,0.001058768,0.00008133802,0.00004880028,0.000201241,0.00006576002,0.0001167255,0.9755949,0.0001884587,0.00009106995,0.005361677],"study_design_scores_gemma":[0.0007962948,0.009585333,0.01928753,0.00002258507,0.0001935065,0.0001915271,0.000258073,0.0008083993,0.9674398,0.0003161295,0.001073887,0.00002683188],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979985,0.0007554615,0.0004272139,0.0001531862,0.00004066218,0.00001490084,0.0001757106,0.00004071336,0.000393605],"genre_scores_gemma":[0.9952456,0.001173716,0.0006540753,0.00008381862,0.0000273148,0.00005067437,0.000230588,0.00001352708,0.002520635],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001968226,"threshold_uncertainty_score":0.006584406,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006489109433836366,"score_gpt":0.2237310492173591,"score_spread":0.2172419397835228,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}