{"id":"W2403979640","doi":"10.1021/jacs.6b03344","title":"Cholesterol Autoxidation Revisited: Debunking the Dogma Associated with the Most Vilified of Lipids","year":2016,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Cholesterol and Lipid Metabolism","field":"Medicine","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Foundation for Innovation","keywords":"Autoxidation; Chemistry; Yield (engineering); Epimer; Stereochemistry; Medicinal chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008779627,0.0007288734,0.001290157,0.002200418,0.002233317,0.004947608,0.002410863,0.007718595,0.002275979],"category_scores_gemma":[0.008107707,0.0004027316,0.00065287,0.001240865,0.02030772,0.01850709,0.004101676,0.02055158,0.00127295],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003178763,"about_ca_system_score_gemma":0.003571364,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00190102,"about_ca_topic_score_gemma":0.003537923,"domain_scores_codex":[0.9981035,0.0006349788,0.0001938841,0.0003451505,0.0005270654,0.0001952852],"domain_scores_gemma":[0.9929625,0.003714728,0.0004928779,0.000610709,0.001644469,0.0005746401],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007126673,0.0002396187,0.002468607,0.004592767,0.0001740927,0.003350626,0.005543438,0.0006523147,0.01299954,0.3343992,0.1998386,0.4350286],"study_design_scores_gemma":[0.00006084401,0.000291055,0.001135061,0.001735065,0.00006296733,0.003474069,0.003662689,0.0005679138,0.004454439,0.2037669,0.7807,0.00008896965],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"commentary","genre_scores_codex":[0.006007662,0.5850452,0.003193333,0.383524,0.01774495,0.00001240445,0.00004290449,0.00009248334,0.004337126],"genre_scores_gemma":[0.07849613,0.6867905,0.003802574,0.1565832,0.06579833,0.00004635512,0.00007621058,0.0001532638,0.008253385],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.008779627,"threshold_uncertainty_score":0.04643166,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01028863631768201,"score_gpt":0.2462513231822406,"score_spread":0.2359626868645586,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}