{"id":"W2404961651","doi":"10.18632/oncoscience.134","title":"BCC or not: Sufu keeps it in check","year":2015,"lang":"en","type":"article","venue":"Oncoscience","topic":"Hedgehog Signaling Pathway Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Hedgehog; PTCH1; Hedgehog signaling pathway; Vismodegib; Biology; Carcinogenesis; Cell biology; Cancer research; Transcription factor; Smoothened; Genetics; Gene; Signal transduction","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005028173,0.00009888134,0.0001098896,0.00003768468,0.00004854711,0.00002057946,0.0002944505,0.00006817069,0.000008754439],"category_scores_gemma":[0.0006943754,0.000079021,0.0000262775,0.0002313454,0.0001602248,0.000004629767,0.0001697065,0.00006284177,0.00005829053],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003297498,"about_ca_system_score_gemma":0.0002862538,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005293087,"about_ca_topic_score_gemma":0.0003258719,"domain_scores_codex":[0.9990242,0.00003406885,0.0001443899,0.0003385182,0.0001911496,0.0002676339],"domain_scores_gemma":[0.9995224,0.00001268253,0.00003837816,0.000251116,0.00006802879,0.0001074009],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001423579,0.000108649,0.009420319,0.00001133178,0.000006719467,0.00004491623,0.0008701726,0.0001331298,0.9729686,0.00008341062,0.01323931,0.002971107],"study_design_scores_gemma":[0.001352214,0.001070103,0.009516154,0.00005085792,0.000007765845,0.00003791701,0.001714251,0.000412885,0.5684746,0.00008518777,0.4167398,0.0005383057],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9892997,0.0002255915,0.0005539965,0.0007057604,0.0003069601,0.0001034035,0.000006786058,0.00001294744,0.008784832],"genre_scores_gemma":[0.9940722,0.00004585306,0.001004719,0.001026868,0.0001135105,0.00001429661,0.00000391448,0.000008102832,0.003710552],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.404494,"threshold_uncertainty_score":0.3222383,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1173336475975667,"score_gpt":0.346696171464374,"score_spread":0.2293625238668073,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}