{"id":"W2404961651","doi":"10.18632/oncoscience.134","title":"BCC or not: Sufu keeps it in check","year":2015,"lang":"en","type":"article","venue":"Oncoscience","topic":"Hedgehog Signaling Pathway Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Hedgehog; PTCH1; Hedgehog signaling pathway; Vismodegib; Biology; Carcinogenesis; Cell biology; Cancer research; Transcription factor; Smoothened; Genetics; Gene; Signal transduction","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006497276,0.0002359009,0.0005260477,0.0004410588,0.000778304,0.00135379,0.0003348039,0.0009537194,0.009862523],"category_scores_gemma":[0.001820228,0.00009941251,0.000221911,0.0002714453,0.0007209195,0.001276942,0.0005568582,0.001640057,0.002992355],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008895603,"about_ca_system_score_gemma":0.0005498231,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001319138,"about_ca_topic_score_gemma":0.00352229,"domain_scores_codex":[0.9995615,0.00005559588,0.00001572221,0.00008944608,0.000188858,0.0000888651],"domain_scores_gemma":[0.9992859,0.0001898892,0.0001071166,0.00005775132,0.0001307921,0.000228631],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001991353,0.0002900028,0.03575309,0.0006957747,0.0001381359,0.003778018,0.0006950233,0.0001798207,0.05341506,0.009027566,0.1480182,0.746018],"study_design_scores_gemma":[0.000163237,0.0014505,0.1031255,0.001516765,0.0003391761,0.02950219,0.002605492,0.001020224,0.02728226,0.02657054,0.806262,0.0001622033],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.4473617,0.1742201,0.008926193,0.1938061,0.01195259,0.0001344611,0.003190697,0.002050327,0.1583578],"genre_scores_gemma":[0.8962532,0.03014995,0.003335401,0.0297179,0.003054007,0.00005654985,0.001332464,0.000429448,0.03567118],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009862523,"threshold_uncertainty_score":0.03299338,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1173336475975667,"score_gpt":0.346696171464374,"score_spread":0.2293625238668073,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}