{"id":"W2404965605","doi":"10.1038/nchembio.2091","title":"Chaperoning for hearing loss","year":2016,"lang":"en","type":"letter","venue":"Nature Chemical Biology","topic":"Hearing, Cochlea, Tinnitus, Genetics","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"","keywords":"Mechanotransduction; Inner ear; Mutant; Cell biology; Transgene; Genetically modified mouse; Component (thermodynamics); Cochlea; Hearing loss; Biology; Anatomy; Genetics; Gene; Medicine; Audiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0001887376,0.000480123,0.0005971206,0.0001406839,0.0001135306,0.00004012692,0.001021244,0.005897179,0.0001130954],"category_scores_gemma":[0.003460982,0.0003752485,0.0002392493,0.0001549731,0.0004634311,0.00003625927,0.0004409408,0.004983258,0.0001701581],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001607826,"about_ca_system_score_gemma":0.0001147348,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002161201,"about_ca_topic_score_gemma":3.198075e-7,"domain_scores_codex":[0.996574,0.0001064581,0.0004082083,0.001407554,0.0002212653,0.001282532],"domain_scores_gemma":[0.9973118,0.001618874,0.0002028582,0.0006559996,0.00009536368,0.0001151564],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002148968,0.000006605782,0.00004692922,0.00008135493,0.000008417128,0.0000366492,0.00001462786,5.860154e-8,0.7502206,0.0004053037,0.2463743,0.0027837],"study_design_scores_gemma":[0.000240825,0.00003928674,0.000002452993,0.00005029685,0.00001001607,0.00005103912,2.976207e-7,0.000006533861,0.406094,0.001164126,0.5920542,0.0002868169],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.03975503,0.001128151,0.0008264935,0.9467356,0.004578843,0.001191477,0.0004815102,0.0005104725,0.00479238],"genre_scores_gemma":[0.09339976,0.0001037567,0.001631005,0.8858705,0.01633378,0.0001020617,0.0001686138,0.0001612212,0.002229318],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.34568,"threshold_uncertainty_score":0.9998699,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03834563762054582,"score_gpt":0.3176044988405922,"score_spread":0.2792588612200463,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}