{"id":"W2406108677","doi":"10.1158/1557-3125.metca15-a83","title":"Abstract A83: Inhibiting mitochondrial ATP synthase with Oligomycin A enhances the kinetics of oncolytic reovirus-induced apoptosis in vitro","year":2016,"lang":"en","type":"article","venue":"Molecular Cancer Research","topic":"Cancer Research and Treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University of Calgary","funders":"","keywords":"Oligomycin; Oncolytic virus; Cancer cell; Viability assay; Biology; ATP synthase; Apoptosis; Programmed cell death; Glycolysis; Cancer research; Biochemistry; Cancer; Metabolism; ATPase; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004188597,0.0002177861,0.0002524268,0.0001875911,0.00009577401,0.0000484491,0.0004579911,0.0001335686,0.00005073069],"category_scores_gemma":[0.0002913743,0.0001287121,0.0001092447,0.0004991089,0.0003601499,0.0000114761,0.000231826,0.0002813581,0.00001122997],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002250212,"about_ca_system_score_gemma":0.0005236897,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003346623,"about_ca_topic_score_gemma":0.001909841,"domain_scores_codex":[0.9971633,0.0002475996,0.0003240064,0.0005793611,0.0009032112,0.0007825217],"domain_scores_gemma":[0.9987,0.000124054,0.0001033818,0.0006097634,0.0002963808,0.0001664573],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002207997,0.000180657,0.0001856318,0.00004820996,0.0001214506,0.00005071987,0.00008150848,0.00001203005,0.9816262,0.00001056445,0.0001523869,0.01532269],"study_design_scores_gemma":[0.002216375,0.0007156427,0.0004470106,0.000253255,0.00001353375,0.000004667905,0.0000894539,0.000003258188,0.9947108,0.00003377763,0.001342299,0.0001698984],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960147,0.0009419401,0.0001785068,0.001212283,0.00005542399,0.0007731001,0.00007777502,0.000007233705,0.0007390915],"genre_scores_gemma":[0.998387,0.000444064,0.0001582978,0.00005594788,0.0001805016,0.0005670302,0.00001556474,0.00004760278,0.0001439442],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01515279,"threshold_uncertainty_score":0.5248726,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03409512203354488,"score_gpt":0.3560555687783531,"score_spread":0.3219604467448082,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}