{"id":"W2406708336","doi":"10.3727/000000004772664833","title":"Transgenic Sertoli Cells as a Vehicle for Gene Therapy","year":2004,"lang":"en","type":"review","venue":"Cell Transplantation","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Genetic enhancement; Transgene; Gene; Sertoli cell; Biology; Genetically modified mouse; Immune system; Gene delivery; Function (biology); Genetically modified organism; Cell therapy; Stem cell; Immunology; Cell biology; Computational biology; Genetics; Spermatogenesis; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004138858,0.0006846008,0.001014333,0.001349566,0.0002173079,0.0008988716,0.0006478504,0.001013047,0.002262629],"category_scores_gemma":[0.000180723,0.0002050812,0.000200106,0.001276663,0.0005203573,0.0007386492,0.0003145768,0.001061647,0.004517499],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004566031,"about_ca_system_score_gemma":0.0004167566,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005253842,"about_ca_topic_score_gemma":0.0008034636,"domain_scores_codex":[0.9998239,0.000025947,0.0000130858,0.00003218825,0.00009293129,0.00001198905],"domain_scores_gemma":[0.9999049,0.00003903744,0.00001408946,0.000006051062,0.00002468279,0.00001127661],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007287534,0.000105937,0.0002026426,0.007344708,0.0000434888,0.0008033058,0.00009475918,0.0006096495,0.08107661,0.01265292,0.0221452,0.8748478],"study_design_scores_gemma":[0.0000149694,0.0000814173,0.0003425551,0.000493985,0.00003005427,0.002154234,0.00003788203,0.0000976619,0.01074668,0.001474078,0.9845119,0.00001449884],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0007450461,0.9894113,0.002552032,0.0002874945,0.0004136961,0.0000152922,0.00003154047,0.00005145583,0.006492059],"genre_scores_gemma":[0.003247699,0.9884495,0.001814371,0.000217763,0.0001364634,0.00002050836,0.00006089979,0.00001004858,0.006042868],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002262629,"threshold_uncertainty_score":0.007569253,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01897032314261755,"score_gpt":0.3301729509654058,"score_spread":0.3112026278227882,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}