{"id":"W2406708336","doi":"10.3727/000000004772664833","title":"Transgenic Sertoli Cells as a Vehicle for Gene Therapy","year":2004,"lang":"en","type":"review","venue":"Cell Transplantation","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Genetic enhancement; Transgene; Gene; Sertoli cell; Biology; Genetically modified mouse; Immune system; Gene delivery; Function (biology); Genetically modified organism; Cell therapy; Stem cell; Immunology; Cell biology; Computational biology; Genetics; Spermatogenesis; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00006794818,0.0003023712,0.0003873068,0.0000527024,0.00005144375,0.00001951945,0.0001658632,0.0003368509,0.00001440064],"category_scores_gemma":[0.00000108775,0.0002843723,0.0004188463,0.00006997262,0.00001654462,0.000002006497,0.000003354769,0.00009118525,0.00002247586],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001648547,"about_ca_system_score_gemma":0.000168483,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007200562,"about_ca_topic_score_gemma":0.000004475507,"domain_scores_codex":[0.9989861,0.00002697612,0.0002865603,0.00038437,0.00008220505,0.0002338001],"domain_scores_gemma":[0.9995981,0.00001689109,0.0000685906,0.0002217761,0.00002779297,0.00006681151],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001541864,0.0001423136,6.012192e-7,0.0414098,0.0002710205,0.00001193131,0.0003737354,0.001102775,0.3814648,0.00001132078,0.00009160913,0.5749659],"study_design_scores_gemma":[0.0008168346,0.0002048783,9.873589e-7,0.0006150911,0.0003107036,0.00002273596,0.00000501996,0.000003655657,0.4351768,0.00001175223,0.5625063,0.0003252685],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001004656,0.962745,0.03473227,0.000003298064,0.0002377124,0.0009251718,0.0001917231,0.00001957647,0.0001406455],"genre_scores_gemma":[0.001232907,0.9947202,0.001003497,0.00002379607,0.0002102554,0.0002016701,0.002126749,0.00008049518,0.0004004634],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.5746406,"threshold_uncertainty_score":0.9999608,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01897032314261755,"score_gpt":0.3301729509654058,"score_spread":0.3112026278227882,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}