{"id":"W2407071357","doi":"10.3182/20100707-3-be-2012.0109","title":"A kinetic modelling approach to study the role of energy regulatory pathways in CHO cells","year":2010,"lang":"en","type":"article","venue":"IFAC Proceedings Volumes","topic":"Viral Infectious Diseases and Gene Expression in Insects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Polytechnique Montréal","funders":"","keywords":"Chinese hamster ovary cell; Pentose phosphate pathway; Metabolic pathway; Glycolysis; Biochemistry; Glutamine; Catabolism; Anabolism; Citric acid cycle; Metabolism; NAD+ kinase; Metabolic network; Biology; Amino acid; Chemistry; Cell biology; Enzyme; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001760768,0.0001590452,0.0001520451,0.00006546923,0.00008591457,0.00003505506,0.0002983665,0.0001153411,0.00000832866],"category_scores_gemma":[0.00002688259,0.0001230312,0.00007729443,0.0001635247,0.00005462251,0.000006543171,0.0001697878,0.0001291574,0.000001960695],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006147857,"about_ca_system_score_gemma":0.00003337988,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001583549,"about_ca_topic_score_gemma":0.0000222842,"domain_scores_codex":[0.9989665,0.000013378,0.0002381195,0.0003760125,0.0001703662,0.0002356265],"domain_scores_gemma":[0.9994591,0.000005078272,0.0000923932,0.0002343018,0.0001157258,0.00009334811],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005658715,0.0004843427,0.01202896,0.00001298846,0.00002729988,2.507089e-7,0.000684383,0.002381097,0.9808506,0.0006015444,0.0004557898,0.002416168],"study_design_scores_gemma":[0.0005999943,0.0004934762,0.005278503,0.00001664265,0.00002827836,0.000005888449,0.001930024,0.01126567,0.9692029,0.001409435,0.009435693,0.0003334764],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949473,0.0002817767,0.0003929345,0.000009506561,0.0001135799,0.0003658962,0.000006180841,0.00001475056,0.00386808],"genre_scores_gemma":[0.9986798,0.00002089829,0.0006558763,0.0000827644,0.0001826048,0.0002063262,0.000004552946,0.00002495405,0.0001422463],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01164767,"threshold_uncertainty_score":0.5017067,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00867089433594558,"score_gpt":0.2129342009472458,"score_spread":0.2042633066113002,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}