{"id":"W2407174002","doi":"10.1016/j.cell.2016.05.003","title":"A Comprehensive, CRISPR-based Functional Analysis of Essential Genes in Bacteria","year":2016,"lang":"en","type":"article","venue":"Cell","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":786,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"National Institute of Biomedical Imaging and Bioengineering; National Institute of General Medical Sciences; National Institute on Drug Abuse; National Institutes of Health","keywords":"Biology; Gene knockdown; CRISPR; Gene; RNA interference; Bacillus subtilis; Computational biology; Functional genomics; Function (biology); Phenotype; Gene regulatory network; Gene knockout; Genetics; Genomics; Gene expression; Cell biology; Bacteria; Genome; RNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00980833278088243,"score_gpt":0.224188237168881,"score_spread":0.2143799043879986,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}