{"id":"W2407186215","doi":"10.1007/978-1-0716-1186-9_11","title":"Isolation of Extracellular Vesicles for Proteomic Profiling","year":2021,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Canadian Institutes of Health Research","keywords":"Proteome; Cell biology; Proteomics; Biology; Microvesicles; Cell; Chemistry; Extracellular vesicles; Biochemistry; Gene; microRNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001101631,0.0001822585,0.0002838757,0.00008453852,0.0000339241,0.000008669586,0.0002243619,0.0003046528,0.00001116892],"category_scores_gemma":[0.001266125,0.0002004578,0.0001916118,0.0001820764,0.0001371592,0.000003315136,0.0001434034,0.0001114123,0.000001044135],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000018023,"about_ca_system_score_gemma":0.0001680023,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000319237,"about_ca_topic_score_gemma":0.000002612765,"domain_scores_codex":[0.9977499,0.0008278246,0.0004871782,0.0005602501,0.00006268841,0.0003121987],"domain_scores_gemma":[0.9989756,0.00007180546,0.0001776802,0.0005444058,0.0001711365,0.00005939097],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001071359,0.0001131113,0.004317162,0.0000824142,0.00005231158,0.00001126066,0.00001848983,0.0001875692,0.9836633,0.004828859,0.000008665502,0.006609744],"study_design_scores_gemma":[0.0007181854,0.0001738792,0.0001959646,0.00001769813,0.00003203644,0.000009331867,0.00003948315,0.0009222153,0.9861736,0.01009158,0.001420697,0.0002053744],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.337591,0.006829255,0.6549051,0.00004991457,0.0001086037,0.0003840528,0.00001798027,0.000007404869,0.0001067584],"genre_scores_gemma":[0.1365649,0.00006169535,0.8626983,0.00007753023,0.00006743913,0.0001454325,0.0002404139,0.00003671237,0.0001075299],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.2077933,"threshold_uncertainty_score":0.8174432,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02140378068069957,"score_gpt":0.3699173084566345,"score_spread":0.3485135277759349,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}